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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Systemic immune response and virus persistence after foot-and-mouth disease virus infection of naïve cattle and cattle vaccinated with a homologous adenovirus-vectored vaccine

Fig. 2

Lymphopenia during acute FMDV infection. a/b non-vaccinated animals, c/d vaccinated animals. Mean lymphocyte counts (black squares), viral load (red circles), and type I/III IFN response (gold diamonds) in peripheral blood (b/d), as well as rectal temperature (purple crosses) and cumulative clinical score (blue triangles) (a/c) are shown with 95 % confidence intervals. The group means for non-vaccinated animals were calculated after individual timescales had been adjusted so that the onset of viremia coincided for all animals (0: first day of viremia). Asterisks mark days on which mean lymphocyte counts were significantly different from the initial value in the fitted model. The limit of detection for the FMDV real-time RT-PCR is 1.6 log10 FMDV GCN/mL

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