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Table 2 Plasma biomarkers of liver damage in dogs, at the initiation (Week -1) and the end (Week 24) of a 24-wk period of consumption of PEGB at 4, 20 or 40 mg/kg/d. (Data are means ± SEM, n = 6/group; minima and maxima values are mentioned in parenthesis)

From: A mixed grape and blueberry extract is safe for dogs to consume

Biomarkers (reference values) Units Control PEGB
4 mg/kg/d 20 mg/kg/j 40 mg/kg/j
Week -1 Week 24 Week -1 Week 24 Week -1 Week 24 Week -1 Week 24
Alanine transaminase (10–118) U/L 38 ± 5 (27–59) 36 ± 5 (26–57) 51 ± 7 (26–60) 44 ± 9 (20–76) 45 ± 2 (39–52) 46 ± 39 (38–61) 41 ± 5 (28–60) 45 ± 4 (28–60)
Alkaline phosphate (20–150) U/L 59 ± 9 (33–88) 63 ± 10 (32–86) 63 ± 6 (49–86) 65 ± 12 (51–126) 55 ± 9 (37–88) 57 ± 14 (33–109) 48 ± 7 (29–78) 49 ± 9 (20–80)