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Table 2 Haplotype frequencies of PRNP in Sicilian autochthonous sheep breedsa

From: Scrapie incidence and PRNP polymorphisms: rare small ruminant breeds of Sicily with TSE protecting genetic reservoirs

PRNP codons

Sheep breeds

136

154

171

Valle del Belice (%)

Comisana (%)

Pinzirita (%)

A

R

Q

58.9

47.8

59.2

A

R

R

32.8

40.4

33.3

 

p-value

 

(0.010)

(0.023)

 

A

R

H

0.8

2.8

-

A

H

Q

5.3

1.7

3.3

V

R

Q

2.2

7.3

4.2

  1. a The analysis was performed on a total of 1395 individuals of Valle del Belice, 1541 Comisana and 84 Pinzirita sheep. The haplotypes are presented in decreasing frequency; in bold are the polymorphic variant amino acid versus wild type (ARQ). For ARR haplotype we performed statistical analysis using Chi Square test with a significant level of p ≤ 0.05. In brackets the p-value results. Statistical analysis in Pinzirita was not performed