Skip to main content

Table 3 Frequency of antiphospholipid antibodies among different groups of dogs based on the 99th percentile cut-off

From: Association of anticardiolipin, antiphosphatidylserine, anti-β2 glycoprotein I, and antiphosphatidylcholine autoantibodies with canine immune thrombocytopenia

aPL subtype I/IA/IB/IC a IIb IIIc I/IA/IB/IC I/IA/IB/IC
n = 64/20/18/26 n = 30 n = 80 vs. II vs. III
positive (%) positive (%) positive (%) relative risk (odds ratio)d, e relative risk (odds ratio)
aPhL 63/20/18/25 (98/100/100/96) 26 (87) 2 (3) 3.5 */(6.9)/(6.2)/2.4 76 ***/(1287)***/(1162)***/73 ***
2GPI 49/17/12/20 (77/85/67/77) 16 (53) 2 (3) 1.4*/1.9*/1.4/1.8 30 ***/24 ***/12 ***/12 ***
aCL 63/19/18/26 (98/95/100/100) 20 (67) 3 (4) 8.3 ***/5.3 */(19)**/(27)*** 74 ***/67 ***/(819)***/(1174)***
aPI 25/8/9/8 (39/40/50/31) 6 (20) 3 (4) 1.3/1.7/2.2/1.3 2.2 ***/5.3 ***/7.1 ***/3.8 ***
aPC 35/12/11/12 (55/60/61/46) 9 (30) 4 (5) 1.3*/2.0 */2.2/1.4 3.2 ***/7.8 ***/8.7 ***/4.8 ***
aPS 45/16/14/15 (70/80/78/58) 13 (43) 4 (5) 1.4*/2.9 */2.7 */1.3 4.5 ***/16 ***/15 ***/6.2 ***
  1. aSubgroups of Group I (thrombocytopenia): IA (immune thrombocytopenia, aPLT+, platelet < 30 × 103/uL), IB (severe thrombocytopenia, aPLT-, platelet < 30 × 103/uL), and IC (less severe thrombocytopenia, platelet 30 – 80 × 103/uL). bGroup II: outpatient dogs without thrombocytopenia. cGroup III: healthy dogs. dOdds ratio is shown in parenthesis if relative risk is ∞. eValue > 2 is shown in bold. *Frequencies are significantly different (* P < 0.05; ** P < 0.01; *** P < 0.001)