Table 1 Demographic variables and outcome measures in the first clinical baseline examination of the placebo and NASHA groups (n = 27) and P-values for the comparison between treatment groups at the first clinical baseline examination

Number of horses

13

14

Age (~years): Mean (range)

8.4 (4–17)

7.2 (4–12)

0.55

Gender: Mare/Stallion/Gelding %

46 %/15 %/39 %

43 %/21 %/36 %

0.09

Purpose: Harness race horse/Riding horse %

54 %/46 %

71 %/29 %

0.44

Breed: Standardbred/Finnhorse/Wamblood/Pony %

31 %/39 %/15 %/15 %

43 %/50 %/7 %/0 %

0.65

Affected limb: RF/LF %

46 %/54 %

71 %/29 %

0.25

Baseline lameness (AAEP)^a: 0/1/2/3/4/5 %

0 %/15 %/39 %/46 %/0 %/0 %

0 %/36 %/57 %/7 %/0 %/0 %

0.05

Effusion^b: 0/1/2/3/4 %

23 %/46 %/0 %/31 %/0 %

29 %/29 %/35 %/7 %/0 %

0.83

Lameness in the flexion test^c: 0/1/2/3/4 %

0 %/0 %/8 %/61 %/31 %

0 %/0 %/29 %/50 %/21 %

0.33

Pain in flexion^d: 0/1/2/3 %

0 %/31 %/23 %/46 %

7 %/29 %/36 %/28 %

0.46

Mild findings in radiographs: Yes/No %

54 %/46 %

50 %/50 %

1.00