From: Thai generic-brand dry canine foods: mutagenicity and the effects of feeding in vivo and in vitro
sample | Amount mg/plate | No. of His+ Revertants/platea | |||
---|---|---|---|---|---|
TA 98, -S9 | TA 98, +S9 | TA100, -S9 | TA 100, +S9 | ||
DG diet | 0 | 32 | 30 | 122 | 110 |
0.1 | 30 | 50 | 91 | 86.5 | |
0.5 | 33 | 41 | 129 | 92 | |
1 | 36.5 | 52 | 114 | 90.5 | |
5 | 19p | 44 | 85p | 84.5 | |
7.5 | ND | 47e | ND | 90.5e | |
10 | 13.5p | 11.5p | ND | 76.5p | |
AP diet | 0 | 28 | 27 | 137 | 110 |
0.01 | 26.5 | ND | 116 | ND | |
0.1 | 25 | 39 | 116.5 | 87 | |
0.5 | 29.5 | 38.5 | 84.5 | 90.5 | |
1 | 55 | 33 | 61p | 87 | |
5 | 25.5p | 33.5 | 76.5p | 81 | |
10 | 26p | 45.5p | 100.5p | 103.5e | |
20 | 31.5p | 30p | 86p | 100e | |
30 | 21p | ND | 105.5p | ND | |
AL diet | 0 | 28 | 30 | 137 | 110 |
0.01 | 66 | ND | 113 | ND | |
0.1 | 63 | 38.5 | 94.5 | 91 | |
0.5 | 64.5p | 49 | 83p | 103 | |
1 | 32p | 56.5 | 94.5p | 107.5 | |
5 | ND | 31.5p | ND | 132.5 | |
10 | ND | 21p | ND | ND | |
RS diet | 0 | 32 | 26 | 137 | 110 |
0.01 | 27 | ND | ND | ND | |
0.1 | 48.5 | 33 | 196.5 | 92 | |
0.5 | 31p | 42.5 | 307.5 | 126 | |
1 | 37.5p | 30 | 262.5 | 138.5 | |
7.5 | ND | 28.5 | 63p | 87.5p | |
10 | ND | ND | 75p | 106.5p | |
NT diet | 0 | 32 | 30 | 108 | 110 |
0.1 | 31.5 | 34.5 | 69.5 | 101.5 | |
0.5 | 28.5 | 63 | 78p | 84.5 | |
1 | 31 | 52.5 | 95.5p | 127.5 | |
2.5 | 13.5 | 33 | ND | 126 | |
5 | 21e | 81p | ND | 109e | |
10 | 13.5p | 58p | ND | ND | |
Positive control | Amount/plate | ||||
4-NQO | 0.2 μg | ND | ND | ND | ND |
0.4 μg | 227.5±3 | ND | ND | ND | |
BAP | 5 μg | ND | ND | 1430±14 | 863±75 |
10 μg | ND | 459±12 | ND | ND | |
AFB1 | 0.03 μg | ND | 130±21 | ND | 241±12 |