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Table 2 Plasma choline levels and hepatic indicators of phosphatidylcholine (PC) metabolism (mean ± SD) in male and female cats before and after spaying/neutering

From: No up-regulation of the phosphatidylethanolamine N-methyltransferase pathway and choline production by sex hormones in cats

  Group 1 (male intact) (n = 6) Group 2 (male neutered) (n = 6) Group 3 (female intact) (n = 6) Group 4 (female spayed) (n = 6)
plasma choline (μM) 1.9 ± 0.8 1.8 ± 0.7 1.5 ± 0.3 2.0 ± 0.5
liver PEMTa activity (nmol/mg protein/h) 0.24 ± 0.18 0.19 ± 0.11 0.15 ± 0.09 0.21 ± 0.16
liver PC content (nmol/mg protein) 24.2 ± 3.8 24.1 ± 3.2 27.5 ± 3.1 24.1 ± 2.3
liver PC 38:6b (% of total PC) 3.3 ± 1.1 3.7 ± 1.6 4.2 ± 0.4 3.8 ± 0.5
liver PC 40:6b (% of total PC) 3.3 ± 1.3 4.2 ± 2.3 4.1 ± 0.6 3.7 ± 0.6
liver PC/PEc ratio 3.4 ± 0.4 3.1 ± 0.3 4.0 ± 1.4 4.0 ± 1.5
  1. a PEMT phosphatidylethanolamine N-methyltransferase
  2. bPC species implicated in PEMT activity i.e. PC containing long highly unsaturated acyl chains
  3. c PE phosphatidylethanolamine
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