Fig. 4
From: Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours
SG2000-induced γH2AX foci/cell in a. CMeC-1 and b. LMeC cell lines following a 1 h treatment with SG2000 and 24 h post-incubation in drug-free medium. Values shown represent the mean percentage distribution of γH2AX foci/cell (50 cells per experiment) from three independent experiments. c. Mean number of foci/cell from CMeC-1 and LMeC cells following treatment for 1 h with SG2000 at the doses shown followed by 24 h post-incubation in drug-free medium. Values are the mean ± SEM from three independent experiments