Regulation effect of Aspirin Eugenol Ester on blood lipids in Wistar rats with hyperlipidemia

BMC Veterinary Research

Table 3 The blood lipids levels at the end of 13th week (after drugs administration for five weeks, n = 10)

Variables	Blank	Model	CMC-Na	Simvastatin	AEE 18	AEE 36	AEE 54	Integration	Aspirin	Eugenol
TG	0.77 ± 0.2^**	1.65 ± 0.22	1.63 ± 0.34	1.12 ± 0.15^**	1.43 ± 0.11	1.36 ± 0.16^*	1.23 ± 0.15^**	1.35 ± 0.17^*	1.27 ± 0.15^**	1.39 ± 0.22
HDL	0.46 ± 0.04	0.52 ± 0.05	0.58 ± 0.02	0.56 ± 0.05	0.55 ± 0.04	0.56 ± 0.03	0.62 ± 0.05^*	0.61 ± 0.02	0.61 ± 0.05	0.56 ± 0.01
LDL	0.11 ± 0.03^**	0.54 ± 0.04	0.51 ± 0.05	0.23 ± 0.04^**	0.31 ± 0.04^**	0.3 ± 0.03^**	0.25 ± 0.04^**	0.31 ± 0.02^**	0.30 ± 0.04^**	0.28 ± 0.05^**
TCH	1.01 ± 0.18^**	2.49 ± 0.14	2.11 ± 0.38	1.61 ± 0.23^**	1.82 ± 0.16^**	1.73 ± 0.21^**	1.55 ± 0.27^**	1.77 ± 0.11^**	1.80 ± 0.10^**	1.68 ± 0.13^**

Note: TG: Triglyceride; HDL: High density lipoprotein; LDL: Low density lipoprotein; TCH: Total cholesterol; Integration: acetylsalicylic acid:eugenol (molar ratio 1:1, 0.11 mmol). The unit of TG, HDL, LDL and TC is mmol/L. ^* P < 0.05 significant difference from model group. ^** P < 0.01 significant difference from model group

ISSN: 1746-6148