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Table 5 Responders in systemic parameters

From: Immune response of healthy horses to DNA constructs formulated with a cationic lipid transfection reagent

Treatment group / horses A) # A # E # I # N # R # W B) # B # F # K # S # O # X C) # C # G # L # P # U # Y D) # D # H # M # Q # V # Z
Age (years) (groups: mean) 11.1 21 4 11 8 13 9 10.6 5 17 19 7 5 10 10.3 2 8 11 8 20 11 10.9 8 8 10 14 17 8
Sex   fe fe mc mc mc mi   fe mc mc fe mc mi   mc mc mc mc mc mi   fe fe mc mc mc mc
Type   ThB WBl WBl WBl WBl ThB   ThB WBl WBl WBl WBl WBl   ThB WBl WBl WBl WBl ThB   ThB WBl WBl WBl WBl WBl
Colour   g g o o o o   g o o o o g   g o g o o o   o g o o g o
Para-meter Thre-shold Period (h)                             
SAA (μg/ml) 10 72 0 3 + + + 3 + + + 2 + +
RT (°C)a 0.5 24 3 + + + 3 + + + 3 + + + 5 + + + + +
Neu (G/l)a 1 24 0 3 + + + 2 + + 2 + +
Lymph (G/l)a -0.4 24 1 + 4 + + + + 2 + + 5 + + + + +
TNFα (pg/ml)b, LPS 5000 24 2 + + 3 + + + 3 + + + 4 + + + +
IFNγ (U/ml)b, med 20 24 0 3 + + + 1 + 2 + +
Responder 1 + 3 + + + 2 + + 4 + + + +
Responses/group parameters with response 6 3 1 1 0 1 0 19 2 0 5 5 5 2 17 1 0 2 0 5 6 20 6 1 3 3 0 6
  1. Numbers of horses that display values of ≥ threshold given in each cell of group columns; response present (+, threshold reached) or absent (−, threshold not reached) given in each cell of individual horses (IDs)
  2. fe female, mare, mc male castrated, gelding, mi male intact, stallion, Wbl Warmblood, ThB thoroughbred, g grey, o other (non-grey), WBC white blood cell counts, Neu neutrophil counts, Lymph lymphocyte counts, med medium settings, LPS LPS settings, responder (response + in min. 3 parameters), response in groups at least two horses +
  3. adifferences to individual time-of-day matched baselines
  4. bdifferences to individual baselines over all times of day