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Table 1 Parameters and coefficients used to calculate clinical scores in BRSV infected calves

From: A bovine respiratory syncytial virus model with high clinical expression in calves with specific passive immunity

Clinical parameter

Parameter coefficient

State description

Numerical value

General state

4

Normal

0

Moves slowly, head down

1

Lying down/staggers

2

Recumbent

3

Appetite

4

Normal

0

Reduced

1

Absent

2

Abdominal dyspnea

3

Normal

0

Slight (short, rapid)

1

Moderate (labored)

2

Severe (very labored, grunting)

3

Rectal temperature

2

<39.6°C

0

<40.0°C

1

<40.5°C

2

<41.0°C

3

≥41.0°C

4

Respiratory rate

2

<50/min

0

<55/min

1

<65/min

2

<75/min

3

≥75/min

4

Intensity of lung sounds

1

Normal

0

Slightly enhanced

1

Moderately enhanced

2

Severely enhanced

3

Added respiratory sounds (wheezing or crackles)

1

Normal

0

Slight

1

Moderate

2

Severe

3

Coughing

1

Absent

0

Only provoked

1

Spontaneous, infrequent

2

Persistent

3

Nasal discharge

1

Normal

0

Slight uni-/bilat. serous

1

Moderate bilat. serous to purulent

2

Copious bilat. purulent

3

  1. During clinical examination, each clinical parameter was assigned a numerical value according to the appropriate state description for that parameter. A clinical score sum was then calculated, by multiplying each numerical value with the parameter coefficient.