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Table 7 Assignment of lesion categories for mesenteric and ileocecal LNN, oGALT and small intestine and in summary

From: Characterization of a caprine model for the subclinical initial phase of Mycobacterium avium subsp. paratuberculosis infection

Lesion category mesenteric and ileocecal LNN oGALT small intestine summary
I no lesions (macroscopic, histological), no MAP no lesions (macroscopic, histological), no MAP no lesions (macroscopic, histological), no MAP all 3 sites (LNN, oGALT and small intestine) are category I
II predominantly small circumscribed lesions, lesions in 1–2 out of the 3 LNN examined, paucibacillary lesions in up to 3 sites of oGALT, f/mf, paucibacillary lesions in up to 2 sites of small intestine, f/mf, paucibacillary at least 2 of the 3 sites (LNN, oGALT, small intestine) are category II or 1 site is category II, 2 are category I or 1 site each is category I, category II and category III
III predominantly extensive lesions, lesions in all 3 LN, pauci-/multibacillary lesions in >3 sites of oGALT, mf, pauci-/ multibacillary lesions in >2 sites of intestine, mf, pauci-/ multibacillary at least 2 of the 3 sites (LNN, oGALT, small intestine) are category III or 1 site is category III and the others are category I
  1. LNN lymph nodes, oGALT gut-associated lymphoid tissue, f focal, mf multifocal.