Start of inoculation period
|
3-5 dpn
|
41-43 dpn
|
---|
Group
|
K1
|
V1
|
V2
|
K2
|
V3
|
V4
|
---|
Number of animals (n)
|
6
|
7
|
7
|
6
|
6
|
7
|
Inoculation dose per day (mg bwm)
|
-
|
10
|
20
|
-
|
10
|
20
|
Average bacterial counts/mL
|
-
|
2.08 ± 0.57x107
|
-
|
1.62 ± 0.73x107
|
Average bacterial counts/inoculum
|
-
|
2.08x108
|
4.16x108
|
-
|
1.62x108
|
3.24x108
|
Total inoculation dose
|
-
|
2.08x109
|
4.16x109
|
-
|
1.62x109
|
3.24x109
|
Time of necropsy (wpi)
|
48a)
|
48
|
49b)
|
46
|
47
|
48c)
|
- dpn, days post natum; bwm, bacterial wet mass; wpi, weeks post infection; a)one animal was necropsied at 39 wpi; b)one animal each died at 37 and 39 wpi, one animal each was necropsied at 37 and 38 wpi; c)one animal was necropsied at 35 wpi.