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Table 6 Study design: group allocation, time point and dose of inoculation and time point of necropsy

From: Characterization of a caprine model for the subclinical initial phase of Mycobacterium avium subsp. paratuberculosis infection

Start of inoculation period 3-5 dpn 41-43 dpn
Group K1 V1 V2 K2 V3 V4
Number of animals (n) 6 7 7 6 6 7
Inoculation dose per day (mg bwm) - 10 20 - 10 20
Average bacterial counts/mL - 2.08 ± 0.57x107 - 1.62 ± 0.73x107
Average bacterial counts/inoculum - 2.08x108 4.16x108 - 1.62x108 3.24x108
Total inoculation dose - 2.08x109 4.16x109 - 1.62x109 3.24x109
Time of necropsy (wpi) 48a) 48 49b) 46 47 48c)
  1. dpn, days post natum; bwm, bacterial wet mass; wpi, weeks post infection; a)one animal was necropsied at 39 wpi; b)one animal each died at 37 and 39 wpi, one animal each was necropsied at 37 and 38 wpi; c)one animal was necropsied at 35 wpi.