Genealogical diagram showing three Hereford calves affected by epidermolysis bullosa and their parents. Males are represented by squares, females by circles, animals of unknown sex are shown rhomboid. Affected animals are shown with fully black symbols and carriers with a half-filled symbol. Note that four of the animals were not genotyped since the DNA was not available (IV/B, II/2, III/B and III/C, indicated with an asterisk). Individuals III/B and III/C are shown with half-filled symbols since they are obligate carriers. The sequenced case is indicated by an arrow.