Efficacy, acceptability and tolerability of the new oral phosphate binder Lenziaren® in healthy cats fed a standard diet

Table 5 Summary of RMANCOVA analyses for all groups (A-F)

Variable	Transformation exponent	Normality P value	P values for model effects in RMANCOVA
			Treatment	Baseline*	Day	Treatment x day interaction	P < 0.05 in post hoc comparisons
Body weight	Log	0.0009	0.0296	< 0.0001	0.8576	0.1674	A, B, C, D & E > F
Food consumed	Log	0.0049	0.3882		0.9961	0.7012	None significant
Serum phosphate concentration	Log	0.0266	0.6387	0.0030	0.5919	0.3622	None significant
Urine phosphate concentration	None	0.5206	0.0337		0.0023	0.0714	D < A, B & E F < E
Phosphorus consumed	None	0.0259	< 0.0001		0.9806	0.7083	F < A, B, C, D & E
Phosphorus excreted in faeces	Log	0.9238	0.0004		< 0.0001	0.1576	F < A, B, C, D & E
Phosphorus excreted in urine	Log	0.0445	0.0196		0.0123	0.1278	D < A & E F < A, B & E
Total phosphorus excreted	Log	0.3241	0.0021		< 0.0001	0.0470	F < A, B, C, D & E
Phosphorus balance	Log	0.0024	0.1410		< 0.0001	0.2730	D < A, B & E
Fractional urinary phosphate excretion	None	0.0187	0.0456		0.0241	0.3375	D < A, B, C & E

*The baseline in the model for variables body weight and serum phosphate concentration was day −30. For all other variables, no baseline was included in the model.
Values in bold indicate statistical significance (P < 0.05).

ISSN: 1746-6148