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Table 2 Phisyological parameters measure during time points by treatment group #

From: Evaluation of the effects of methadone and tramadol on postoperative analgesia and serum interleukin-6 in dogs undergoing orthopaedic surgery

   Time TBL point T1 T2 T4 T6 T24
HR TRA 136 ± 25 123 ± 12 101 ± 25b 121 ± 25b 143 ± 25*,a,b 151 ± 27a
  MET 0.5 133 ± 25 107 ± 30* 83 ± 20* 110 ± 26b 106 ± 27* 121 ± 8
  MET 0.7 140 ± 23 117 ± 16 64 ± 17* 86 ± 26* 105 ± 17* 140 ± 14
RR TRA 56 ± 9 46 ± 11* 10 ± 2* 26 ± 13* 36 ± 18* 55 ± 10
  MET 0.5 52 ± 13 55 ± 15* 10 ± 2* 31 ± 21* 41 ± 17* 60 ± 10
  MET 0.7 58 ± 7 60 ± 5* 10 ± 2* 25 ± 14* 39 ± 14* 52 ± 18
SAP TRA 183 ± 15 161 ± 17b 106 ± 17* 156 ± 25* 163 ± 24 176 ± 17a
  MET 0.5 168 ± 24 146 ± 43b 90 ± 17* 147 ± 19 147 ± 23 173 ± 10
  Met 0.7 179 ± 23 187 ± 21 98 ± 20* 120 ± 34 170 ± 23 165 ± 40
MAP TRA 121 ± 3 128 ± 18 89 ± 19* 104 ± 28 119 ± 25 140 ± 26
  MET 0.5 126 ± 19 109 ± 31b 77 ± 13* 108 ± 23 108 ± 23 123 ± 9
  MET 0.7 134 ± 24 137 ± 18 74 ± 14* 110 ± 21* 124 ± 21 122 ± 14
DAP TRA 91 ± 5 111 ± 5a 78 ± 17 87 ± 26 92 ± 23 100 ± 5a
  MET 0.5 100 ± 19 85 ± 28b 60 ± 12 60 ± 18 87 ± 23 77 ± 12b
  MET 0.7 106 ± 22 107 ± 18 58 ± 14 84 ± 16 96 ± 21 100 ± 18
  1. #HR: Heart rate in beats per minute; RR: Respiratory rate in breaths per minute; SAP, MAP and DAP: Systolic, Mean and Diastolic arterial pressures in mmHg.
  2. *:differs from TBL; a: differs from MET 0.5, b: differs from MET 0.7; p < 0.05.