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Table 1 Determination of IC 50 values for mavacoxib and carprofen in normal keratinocytes (CPEK); osteosarcoma (D17, KTOSA5, CSKOS); glioma (J3T); lymphoma (3132); mast cell tumour (C2-S); and haemangiosarcoma (SB) cell lines

From: The long-acting COX-2 inhibitor mavacoxib (Trocoxil™) has anti-proliferative and pro-apoptotic effects on canine cancer cell lines and cancer stem cells in vitro

 

IC50

Cell type

Mavacoxib

Carprofen

CPEK

87.1 μM

226.6 μM

D17

152.7 μM

225.6 μM

KTOSA5

93.4 μM

172.1 μM

CSKOS

107.8 μM

167 μM

J3T

68.4 μM

239.8 μM

3132

36.5 μM

63.5 μM

C2-S

29.3 μM

93.5 μM

SB

63.5 μM

70.4 μM

  1. All measurements were made in triplicate.