Figure 2From: The long-acting COX-2 inhibitor mavacoxib (Trocoxil™) has anti-proliferative and pro-apoptotic effects on canine cancer cell lines and cancer stem cells in vitroEffects of NSAIDs on apoptosis. CPEK, CSKOS, and KTOSA5 cells were treated with the indicated doses of either carprofen or mavacoxib. Annexin V-FITC staining was analysed by FACS 24 hours and 48 hours after treatment. The percentage of Annexin V positive cells was quantified. Y p = 0.02, * p = 0.01, * p = 0.002, * p < 0.001 by comparing the indicated drug concentration at the indicated time point to the untreated control by a student's t-test.Back to article page