Skip to main content

Table 3 Under-represented cellular pathways in canine mammary cancer

From: Gene expression profiles in canine mammary carcinomas of various grades of malignancy

Cellular pathways 1vs 2 1vs 3 2vs 3
5HT1 type receptor mediated signaling pathway   X X
Alzheimer disease-amyloid secretase pathway X X  
Alzheimer disease-presenilin pathway X X  
Angiogenesis X X  
Apoptosis signaling pathway X X  
B cell activation X X  
Beta1 adrenergic receptor signaling pathway   X X
Beta2 adrenergic receptor signaling pathway   X X
Cadherin signaling pathway X X  
EGF receptor signaling pathway X X  
Endothelin signaling pathway X X X
GABA-B_receptor_II_signaling   X X
Glycolysis X X  
Hedgehog signaling pathway   X X
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway   X X
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway X   X
Histamine H2 receptor mediated signaling pathway   X X
Huntington disease X X  
Hypoxia response via HIF activation   X X
Inflammation mediated by chemokine and cytokine signaling pathway X X  
Metabotropic glutamate receptor group II pathway   X X
Metabotropic glutamate receptor group III pathway   X X
Muscarinic acetylcholine receptor 2 and 4 signaling pathway   X X
Oxidative stress response X X X
PDGF signaling pathway X X  
Parkinson disease X X  
T cell activation X X  
Thyrotropin-releasing hormone receptor signaling pathway X   
Transcription regulation by bZIP transcription factor   X X
Wnt signaling pathway X X  
p53 pathway by glucose deprivation X X  
  1. Cellular pathways in which are involved significantly down-regulated genes in the examined tumour groups. The analysis was conducted using PANTHER Database (http://www.pantherdb.org). The pathway activity in the tumour group 1 vs 2, 1 vs 3 and 2 vs 3 is marked as X.