Kinetics of the porcine reproductive and respiratory syndrome virus (PRRSV) humoral immune response in swine serum and oral fluids collected from individual boars

Table 3 Comparison of cumulative quantitative reverse transcription polymerase chain reaction (qRT-PCR) and antibody responses (IgM, IgA, IgG) for 21 days following PRRSV inoculation ¹

	Serum (mean AUC and 95% confidence intervals)				Oral fluid (mean AUC and 95% confidence intervals)
Trial (virus isolate)	qRT-PCR	IgM	IgA	IgG	qRT-PCR	IgM	IgA	IgG
Trial 1: (Ingelvac® PRRS MLV)	21.6^b	46.6^b	18.5^b	17.4^a	21.0^b	27.6^b	12.3^b	25.1^b
Trial 1: (Ingelvac® PRRS MLV)	(18.8-24.5)	(43.1-50.2)	(14.6-22.6)	(15.9-18.9)	(17.0-25.1)	(23.9-31.5)	(7.7-17.0)	(20.6-29.6)
Trial 2: (Type 1, D09-012332)	23.8^b	39.5^b	30.0^a	18.3^a	21.2^b	17.6^c	17.9^b	21.9^b
Trial 2: (Type 1, D09-012332)	(21.2-26.6)	(31.1-48.0)	(23.2-36.9)	(16.5-20.2)	(18.1-24.3)	(12.0-23.2)	(10.9-24.9)	(16.7-27.2)
Trial 3: (Type 2, MN-184)	38.1^a	53.7^a	31.6^a	18.4^a	31.6^a	35.4^a	26.2^a	30.1^a
Trial 3: (Type 2, MN-184)	(34.9-41.5)	(48.1-59.3)	(24.7-38.5)	(17.1-19.85)	(28.4-34.9)	(28.6-42.3)	(19.1-33.5)	(25.3-34.9)

¹ Individual boar PRRSV (log_e geq/μl) and antibody (IgM, IgA, IgG) S/P responses over time were summarized as the area under the curve (AUC) prior to performing the statistical analysis.
^abc Superscripts within columns indicate statistically significant differences among means (Tukey’s Honestly Significant Differences test, p < 0.05).

ISSN: 1746-6148