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Table 3 Staphylococcus aureus IMI eligible for 8-day lactation therapy in treatment and control pens

From: Effect of lactation therapy on Staphylococcus aureus transmission dynamics in two commercial dairy herds

Treatment Pen
  All Subclinical treated Cure1following subclinical therapy Right censor reason2 Quarter with Clinical events
     exit dry cull Study end IMI started as clinical case Flare-up during existing IMI
Farm 1 13 13 10 0 0 1 2 1 1
Farm 2 9* 5 4 3 1 1 0 0 0
Total 22 18 14 3 1 2 2 1 1
Control Pen
  All Subclinical treated Spontaneous cure 3 Right censor reason 2 Quarter with Clinical events
     exit dry cull Study end IMI started as clinical case Flare-up during existing IMI
Farm 1 16 nt4 0 0 6 1 9 3 8
Farm 2 0 nt 0 0 0 0 0 0 0
Total 16 nt 0 0 6 1 9 3 8
  1. 1 Bacteriologic cure following treatment of subclinical or clinical IMI is based on negative bacteriologic culture for the pre-treatment Pulsotype (PT) on 4 of 4 samples taken at approximately 7, 14, 21, and 28 days post-treatment.
  2. 2 Right censored IMI are classified to include all IMI that are not cured prior to either exit from a study pen to another lactating group (exit), dry-off (dry), culling (cull), or at the conclusion of the study (study end).
  3. 3 Spontaneous cure of an IMI is based on 2 sequential negative monthly cultures for the prior PT.
  4. 4 nt = not treated, i.e. subclinical IMI that would have been eligible for therapy in control pens but were not treated.
  5. * 4 quarters in the treatment group were eligible for subclinical therapy but exited the study pen prior to initiation of therapy (3 exited to another pen and 1 dry-off).