Table 1 Medians, p-values and interquartile range (p25; p75) values of hemostatic profile on pre (M0) and post-treatment (M1) moments of groups I and II

Platelet aggregation (%)

73.00 (71.25;81.5)

81.00 (p = 0.41) (78.03;86)

64.50 (61;86.75)

83.00* (p = 0.03) (77.5;92.25)

Antithrombin (%)

92.3 (87.32;95.05)

76.25* (p = 0.02) (71.48;82.18)

125.25 (106.15;132.15)

77.3* (p = 0.005) (71.67;82.07)

Cortisol (μg/dL)

1.19 (0.97;1.31)

3.28* (p = 0.003) (2.65;7.46)

1.97 (1.38;3.21)

14.97* (p = 0.003) (5.66;21.59)

Factor VIII (%)

110.33 (93.19;171.57)

88.38 (p = 0.36) (60.55;93.19)

161.35 (90.89;243.80)

151.96 (p = 0.77) (135.09;160.36)

Fibrinogen (mg/dL)

234.52 (186.14;234.52)

298.08 (p = 0.30) (158.19;328.21)

234.52 (183.53;348.66)

184.09 (p = 0.09) (162.19;205.77)

vWF (%)

187.58 (148.76;241.42)

111.14* (p = 0.049) (82.9;142.46)

112.21 (100.19;133.48)

79.88 (p = 0.14) (59.09;136.26)

FDP (mg/dL)

0 (0;1)

0 (p = 0.62) (0;2)

1.50 (0.25;2)

1.50 (p = 1.00) (1;2)

Platelets (/μL)

228.000 (204.000;292.500)

226.500 (p = 0.56) (195.250;343.250)

294.500 (217.031;421.000)

348.000 (p = 0.84) (261.750;387.387)

PT (s)

11.80 (11.03;13.05)

10.50 (p = 0.15) (9.7;11.2)

9.90 (9;10.4)

8.50 (p = 0.09) (7.5;9.95)

OMBT (s)

74.50 (59.5;88.75)

86.00 (p = 0.22) (62.25;107.5)

80.00 (55;84.25)

75.50 (p = 0.62) (66.25;100)

TT (s)

14.75 (12.25;17.25)

10.38 (p = 0.07) (9.70;11.40)

11.30 (9.7;12.5)

9.65 (p = 0.18) (9.08;9.98)

aPTT (s)

18.00 (15.75;19.21)

16.00 (p = 0.62) (15.23;18)

14.00 (13.8;14.9)

14.70 (p = 0.64) (13.4;16.23)