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Table 1 Medians, p-values and interquartile range (p25; p75) values of hemostatic profile on pre (M0) and post-treatment (M1) moments of groups I and II

From: Hemostatic profile and thromboembolic risk in healthy dogs treated with prednisone: a randomized controlled trial

  M0 M1 M0 M1
Platelet aggregation (%) 73.00 (71.25;81.5) 81.00 (p = 0.41) (78.03;86) 64.50 (61;86.75) 83.00* (p = 0.03) (77.5;92.25)
Antithrombin (%) 92.3 (87.32;95.05) 76.25* (p = 0.02) (71.48;82.18) 125.25 (106.15;132.15) 77.3* (p = 0.005) (71.67;82.07)
Cortisol (μg/dL) 1.19 (0.97;1.31) 3.28* (p = 0.003) (2.65;7.46) 1.97 (1.38;3.21) 14.97* (p = 0.003) (5.66;21.59)
Factor VIII (%) 110.33 (93.19;171.57) 88.38 (p = 0.36) (60.55;93.19) 161.35 (90.89;243.80) 151.96 (p = 0.77) (135.09;160.36)
Fibrinogen (mg/dL) 234.52 (186.14;234.52) 298.08 (p = 0.30) (158.19;328.21) 234.52 (183.53;348.66) 184.09 (p = 0.09) (162.19;205.77)
vWF (%) 187.58 (148.76;241.42) 111.14* (p = 0.049) (82.9;142.46) 112.21 (100.19;133.48) 79.88 (p = 0.14) (59.09;136.26)
FDP (mg/dL) 0 (0;1) 0 (p = 0.62) (0;2) 1.50 (0.25;2) 1.50 (p = 1.00) (1;2)
Platelets (/μL) 228.000 (204.000;292.500) 226.500 (p = 0.56) (195.250;343.250) 294.500 (217.031;421.000) 348.000 (p = 0.84) (261.750;387.387)
PT (s) 11.80 (11.03;13.05) 10.50 (p = 0.15) (9.7;11.2) 9.90 (9;10.4) 8.50 (p = 0.09) (7.5;9.95)
OMBT (s) 74.50 (59.5;88.75) 86.00 (p = 0.22) (62.25;107.5) 80.00 (55;84.25) 75.50 (p = 0.62) (66.25;100)
TT (s) 14.75 (12.25;17.25) 10.38 (p = 0.07) (9.70;11.40) 11.30 (9.7;12.5) 9.65 (p = 0.18) (9.08;9.98)
aPTT (s) 18.00 (15.75;19.21) 16.00 (p = 0.62) (15.23;18) 14.00 (13.8;14.9) 14.70 (p = 0.64) (13.4;16.23)
  1. vWF: von Willebrand Factor; FDP: Fibrin degradation products; PT: Prothrombin time; OMBT: Oral mucosa bleeding time; TT: Thrombin time; aPTT: Activated Partial Thromboplastin time. *Statistical difference (p < 0,05).