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Table 4 Mean total multi-dose propofol (MDP) required for induction of anesthesia, grouped by premedicant 1

From: Multicenter clinical evaluation of a multi-dose formulation of propofol in the dog

Premedicant

None

Midazolam

Acepromazine

Medetomidine

Number of animals

23

47

45

20

Total MDP dose (mg/kg) 2

7.55

4.70

4.00

3.15

Standard deviation

2.14

1.34

0.95

1.38

Range

4.6-16.0

2.2-8.3

1.8-5.1

1.7-7.5

  1. 1Sedative and tranquilizers given in combination with buprenorphine; use of anticholinergics was optional. See text for additional detail.
  2. 2Statistically significant (p < 0.05) differences: None > (Midazolam, Acepromazine and Medetomidine) and Midazolam > Medetomidine.