Table 2 Effects of rt-PA on haemostasis and further blood parameters (reference values in parentheses) in 6 horses of the main experiment (mean ± SD), *significantly different from basal value (p < 0.05)
Time (h) | Thrombin time (sec; 17–21) | Prothrombin time (%; 70–100) | Partial thromboplastin time (sec; 43–63) | Fibrinogen (g/l; 1.0-1.2) | Thrombocytes (103/μl; 90–300) | White blood cells (G/l; 5–10) | Red blood cells (T/l; 6.5-9.0) | Haematocrit (%; 32–45) |
|---|---|---|---|---|---|---|---|---|
0 | 18.67 (±1.97) | 85.50 (±15.23) | 55.67 (±7.94) | 1.13 (±0.16) | 120.50 (±44.60) | 7.67 (±1.06) | 7.31 (±0.99) | 36.83 (±3.19) |
1 | 18.17 (±1.47) | 93.50 (±10.46) | 51.67 (±5.96) | 1.12 (±0.13) | 132.50 (±37.18) | 7.45 (±1.23) | 7.64 (±0.48) | 37.50 (±3.15) |
2 | 17.17 (±1.33) | 97.00 (±4.69) | 47.50 (±8.04) | 1.14 (±0.19) | 126.00 (±37.46) | 7.32 (±1.23) | 7.59 (±0.51) | 37.00 (±2.83) |
3 | 18.17 (±1.72) | 88.83 (±15.69) | 48.83 (±5.74) | 1.13 (±0.14) | 128.50 (±34.05) | 8.00 (±0.79) | 8.04 (±0.85) | 40.15 (±5.02) |
4 | 17.67 (±1.37) | 95.00 (±7.75) | 45.17 (±6.40)* | 1.13 (±0.17) | 126.50 (±32.02) | 7.75 (±1.07) | 7.74 (±0.50) | 38.63 (±2.94) |
5 | 17.50 (±1.64) | 90.33 (±14.72) | 50.17 (±8.77) | 1.09 (±0.13) | 114.00 (±23.82) | 7.95 (±1.38) | 7.85 (±0.52) | 39.17 (±3.54) |
12 | 19.67 (±1.51) | 89.00 (±13.77) | 55.00 (±6.16) | 1.08 (±0.11) | 150.17 (±41.73) | 7.67 (±1.50) | 7.95 (±0.45) | 39.30 (±2.07) |
24 | 18.50 (±0.84) | 89.33 (±16.54) | 54.83 (±5.19) | 1.10 (±0.16) | 127.83 (±44.20) | 8.02 (±1.19) | 8.22 (±1.10) | 41.33 (±4.46) |
36 | 18.50 (±0.84) | 87.17 (±20.77) | 57.17 (±6.21) | 1.15 (±0.14) | 139.33 (±37.89) | 7.73 (±1.57) | 8.54 (±1.03) | 41.33 (±3.44) |
48 | 18.50 (±1.05) | 85.17 (±20.22) | 56.33 (±6.77) | 1.13 (±0.12) | 132.67 (±36.66) | 7.62 (±1.06) | 8.01 (±0.66) | 38.73 (±3.44) |