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Table 2 Effects of various heat treatments in yellow grease on BSE-infected spinal cord homogenates

From: Rapid assessment of bovine spongiform encephalopathy prion inactivation by heat treatment in yellow grease produced in the industrial manufacturing process of meat and bone meals

Temperature Time (h) Transmission rate (diseased/total) Mean incubation time ± SD (days) Log reduction of infectivity Log reduction of PMCA50
140°C 1 100% (6/6) 304 ± 13*,‡ 1.54 2.75
  3 83% (5/6) 382 ± 64, >790 >3.0 4.0
160°C 1 67% (4/6) 471 ± 80*,†, >790 >3.0 3.5
  3 17% (1/6) 514, >790 >3.0 6.0
180°C 1 100% (6/6) 380 ± 25†,‡ >3.0 3.25
  3 0% (0/6) >790 >3.0 6.75
  1. *,†,‡ Significant differences (*: p < 0.01; †, ‡: p < 0.05) were observed among mice with respect to the mean incubation times as indicated by identical superscript character.