Skip to main content

Table 4 Best concentration-time equations of ciprofloxacin in grass carp

From: Integrated pharmacokinetics/pharmacodynamics parameters-based dosing guidelines of enrofloxacin in grass carp Ctenopharyngodon idella to minimize selection of drug resistance

Dose

Tissues

Equation

10 μg/g

Serum

C = 0.119e-0.010t + 0.119e-0.078t

Liver

C = 0.178e-0.008t + 0.178e-0.249t

Muscel

C = 0.048e-0.001t + 0.048e-0.171t

Kidney

C = 0.125e-0.011t + 0.125e-0.202t

20 μg/g

Serum

C = 0.175e-0.009t + 0.175e-0.268t

Liver

C = 0.451e-0.008t + 0.451e-0.222t

Muscel

C = 0.188e-0.003t + 0.188e-0.171t

Kidney

C = 0.222e-0.012t + 0.222e-0.214t

30 μg/g

Serum

C =0.209e-0.007t + 0.209e-0.248t

Liver

C = 0.710e-0.007t + 0.710e-0.217t

Muscel

C = 0.260e-0.005t + 0.260e-0.222t

 

Kidney

C = 0.488e-0.015t + 0.488e-0.211t