Oxidative stress in cancer-bearing dogs assessed by measuring serum malondialdehyde

BMC Veterinary Research

Table 3 Malondialdehyde, complete blood counts and blood chemistry parameters for cancer-bearing dogs and clinically normal dogs

Variables	Cancer-bearing dogs (N = 80)	Clinically normal dogs (N = 101)	p-value^a	Adjusted p-value^b	Normal ranges[28]
MDA, mean ± SD, μmol/L	4.68 ± 1.32	2.95 ± 0.61	<0.001	<0.001
PCV, mean ± SD, %	36.18 ± 7.65	44.84 ± 5.54	<0.001	<0.001	37-55
Hemoglobin, mean ± SD, g%	11.93 ± 2.88	15.17 ± 2.00	<0.001	<0.001	12-18
RBC, median (IQA), 10⁶/μL	6.05 (2.15)	8.09 (1.34)	<0.001	NA	5.5-8.5
WBC, median (IQA), 10³/μL	18.20 (11.95)	14.90 (5.10)	<0.001	NA	6-17
Creatinine, median (IQA), mg/dL	0.90 (0.30)	1.00 (0.25)	0.312	NA	0.9-1.7
ALT, median (IQA), U/L	32.00 (33.00)	36.00 (26.00)	0.395	NA	10-120

Abbreviations: ALT alanine aminotransferase, MDA malondialdehyde, NA not applicable, PCV packed cell volume, IQA interquartile range, RBC red blood cells, SD standard deviation, U/L unit per liter, WBC white blood cells.
^aAn independent sample Students t-test was used for MDA, PCV, and hemoglobin, while a Mann–Whitney U test was used for RBC, WBC, creatinine, and ALT.
^bAdjusted p-values were obtained from an analysis of covariance using the age of dogs as a covariate.

ISSN: 1746-6148