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Table 3 Malondialdehyde, complete blood counts and blood chemistry parameters for cancer-bearing dogs and clinically normal dogs

From: Oxidative stress in cancer-bearing dogs assessed by measuring serum malondialdehyde

Variables Cancer-bearing dogs
(N = 80)
Clinically normal dogs
(N = 101)
p-valuea Adjusted p-valueb Normal ranges[28]
MDA, mean ± SD, μmol/L 4.68 ± 1.32 2.95 ± 0.61 <0.001 <0.001  
PCV, mean ± SD, % 36.18 ± 7.65 44.84 ± 5.54 <0.001 <0.001 37-55
Hemoglobin, mean ± SD, g% 11.93 ± 2.88 15.17 ± 2.00 <0.001 <0.001 12-18
RBC, median (IQA), 106/μL 6.05 (2.15) 8.09 (1.34) <0.001 NA 5.5-8.5
WBC, median (IQA), 103/μL 18.20 (11.95) 14.90 (5.10) <0.001 NA 6-17
Creatinine, median (IQA), mg/dL 0.90 (0.30) 1.00 (0.25) 0.312 NA 0.9-1.7
ALT, median (IQA), U/L 32.00 (33.00) 36.00 (26.00) 0.395 NA 10-120
  1. Abbreviations: ALT alanine aminotransferase, MDA malondialdehyde, NA not applicable, PCV packed cell volume, IQA interquartile range, RBC red blood cells, SD standard deviation, U/L unit per liter, WBC white blood cells.
  2. aAn independent sample Students t-test was used for MDA, PCV, and hemoglobin, while a Mann–Whitney U test was used for RBC, WBC, creatinine, and ALT.
  3. bAdjusted p-values were obtained from an analysis of covariance using the age of dogs as a covariate.