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Table 2 Serum antibody levels at the different treatments

From: Vaccination prepartum enhances the beneficial effects of melatonin on the immune response and reduces platelet responsiveness in sheep

Treatment    Day   
0 21 42 60 90
I. Control 13 ± 2 12 ± 3 14 ± 3 16 ± 4 15 ± 3
II. Melatonin Implant 12 ± 2 16 ± 3 14 ± 4 13 ± 3 15 ± 2
III. Vaccine 16 ± 3 40 ± 6*† 90 ± 5*† 104 ± 4*† 70 ± 5*†
IV. Vaccine + Melatonin Implant 14 ± 3 52 ± 5*†§† 112 ± 6*†§† 141 ± 5*†§† 97 ± 4*†§†
  1. Values represent mean antibodies levels as determined by microagglutination assays. Data are presented as mean ± S.E.M. of 10 experiments. *P < 0.05 compared with day 0. P < 0.05 compared with their respective control in nonvaccinated animals. §P < 0.05 compared with the application of melatonin implants. P < 0.05 compared with vaccinated animals.