a) Classification of pigs based on disease severity assessed by CT score and radiographic score on day 7 post challenge | |||||
CT score on day 7 post challenge | radiographic score* on day 7 post challenge | ||||
not affected 0–4 | slightly affected 5–15 | moderately affected 16–26 | severely affected > 26 | Total | |
severely affected (≥2.23) | 0 | 5 (17. 2%) | 2 (6.9%) | 2 (6.9%) | 9 (31.0%) |
moderately affected (1.71–2.22) | 0 | 0 | 2 (6.9%) | 0 | 2 (6.9%) |
slightly affected (0.24–1.70) | 3 (10.3%) | 4 (13.8%) | 1 (3.5%) | 0 | 8 (27.6%) |
not affected (0–0.23) | 8 (27.6%) | 2 (6. 9%) | 0 | 0 | 10 (34.5%) |
Total | 11 (37.9%) | 11 (37.9%) | 5 (17.3%) | 2 (6.9%) | 29 (100.00%) |
b) Classification of pigs based on disease severity assessed by CT score and radiographic score on day 21 post challenge | |||||
CT score on day 21 post challenge | radiographic score* on day 21 post challenge | ||||
not affected 0–4 | slightly affected 5–15 | moderately affected 16–26 | severely affected > 26 | Total | |
severely affected (≥ 2.23) | 0 | 0 | 2 (7.4%) | 0 | 2 (7.4%) |
moderately affected (1.71–2.22) | 1 (3.7%) | 2 (7.4%) | 0 | 0 | 3 (11.1%) |
slightly affected (0.24–1.70) | 1 (3.7%) | 7 (26.0%) | 2 (7.4%) | 0 | 10 (37.1%) |
not affected (0–0.23) | 8 (29.6%) | 4 (14.8%) | 0 | 0 | 12 (44.4%) |
Total | 10 (37.0%) | 13 (48.2%) | 4 (14.8%) | 0 | 27 (100.00%) |
c) Classification of pigs based on disease severity assessed by CT score and lung lesion score | |||||
CT score on day 21 post challenge | lung lesion score** on day 21 post challenge | ||||
not affected 0 | slightly affected 0.1–5.0 | moderately affected 5.1–10.0 | severely affected > 10 | Total | |
severely affected (≥ 2.23) | 0 | 0 | 0 | 4 (13.8%) | 4 (13.8%) |
moderately affected (1.71–2.22) | 0 | 0 | 3 (10.4%) | 0 | 3 (10.4%) |
slightly affected (0.24–1.70) | 0 | 7b (24.1%) | 3 (10.3%) | 0 | 10 (34.4%) |
not affected (0–0.23) | 10a (34.5%) | 1b (3.5%) | 1b (3.4%) | 0 | 12 (41.4%) |
Total | 10 (34.5%) | 8 (27.6%) | 7 (24.1%) | 4 (13.8%) | 29 (100.0%) |
d) Classification of pigs based on disease severity assessed by radiographic score and lung lesion score | |||||
radiographic score* on day 21 post challenge | lung lesion score** on day 21 post challenge | ||||
not affected 0 | slightly affected 0.1–5.0 | moderately affected 5.1–10.0 | severely affected > 10 | Total | |
severely affected>26 | 0 | 0 | 0 | 2 (6.9%) | 2 (6.9%) |
moderately affected16–26 | 0 | 1 (3.5%) | 1 (3.5%) | 2 (6.9%) | 4 (13.8%) |
slightly affected5–15 | 4 (13.8%) | 5b (17.2%) | 4 (13.8%) | 0 | 13 (44.8%) |
not affected0–4 | 6a (20.7%) | 2b (6.9%) | 2b (6.9%) | 0 | 10 (34.5%) |
Total | 10 (34.5%) | 8 (27.6%) | 7 (24.1%) | 4 (13.8%) | 29 (100.00%) |