Erythrocyte Pyruvate Kinase Deficiency mutation identified in multiple breeds of domestic cats

BMC Veterinary Research

Table 2 Pyruvate kinase deficiency allele frequencies in cat breeds and populations

Breed	Samples	GG	GA	AA	Freq. A	Exp GG	Exp GA	Exp AA
Abyssinian*	1955	1476	465	14	0.126	1493	431	31
Abyssinian (UK)	36	28	8	0	0.11	29	7	0
American Bobtail	10	10			0
American SH	51	51			0
American Wirehair	11	11			0
Australian Mist (UK)	27	27			0
Balinese	39	39			0
Bengal*	1340	925	390	25	0.164	936	368	36
Bengal (UK)	1210	827	354	29	0.17	834	341	35
Birman	187	187			0
British SH	966	966			0
British SH (UK)	43	43			0
Burmese	118	118			0
Burmilla	38	38			0
Cornish Rex	46	46			0
Devon Rex	186	186			0
Domestic SH/LH	76	62	13	1	0.099	62	13	1
Egyptian Mau	36	27	9	0	0.1	28	8	1
Exotic LH	91	91			0
Exotic SH	645	644	1	0	0.0008	644	1	0
Himalayan	601	601			0
Korat	41	41			0
La Perm	56	40	16	0	0.14	41	14	1
Maine Coon	118	103	15	0	0.064	104	14	0
Munchkin	19	19			0
Norwegian Forest Cat	13	10	3	0	0.1	10	3	0
Ocicat	69	69			0
Oriental LH	48	48			0
Oriental SH	337	336	1	0	0.001	336	1	0
Persian	2226	2217	9	0	0.002	2217	9	0
Ragamuffin	20	20			0
Ragdoll	1063	1063			0
Russian Blue	14	14			0
Savannah Cat	11	10	1	0	0.05	10	1	0
Scottish Fold	68	68
Selkirk Rex	124	124
Siamese	457	457
Siberian Cat	377	360	16	1	0.024	359	18	0
Singapura	150	88	55	7	0.23	89	53	8
Singapura (UK)	168	60	77	31	0.414	58	81	29
Somali	633	527	104	2	0.0853	530	99	5
Somali (UK)	65	49	14	2	0.14	48	16	1
Sphynx	248	248
Turkish Angora	31	31
Unreported	111	98	13	0	0.059	99	12	0
Total	14179	12503	1564	112	0.063051	12447	1675	56

ISSN: 1746-6148