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Table 3 Univariable relative risk ratios and odds ratios for each of having one or two ears affected by congenital hereditary sensorineural deafness (CHSD) rather than no ears affected in Australian Cattle Dogs from multinomial logistic models and cumulative proportion animal models

From: Prevalence of congenital hereditary sensorineural deafness in Australian Cattle Dogs and associations with coat characteristics and sex

Variable Multinomial logistic model* Multinomial cumulative proportion animal model**
  One ear affected Two ears affected Odds ratio (95% CI)† P-value***
  Relative risk ratio (95% CI)† P-value*** Relative risk ratio (95% CI)† P-value***
Sex     0.155   0.069
 Male Reference category   Reference category   Reference category  
 Female 1.7 (1.0 to 2.8) 0.056 1.4 (0.6 to 3.0) 0.447 1.6 (1.0 to 2.5) 0.067
Colour     0.913   0.940
 Red Reference category   Reference category   Reference category  
 Blue 0.9 (0.4 to 2.1) 0.857 1.5 (0.6 to 4.2) 0.402 1.1 (0.5 to 2.2) 0.878
 Blue black tan 0.9 (0.5 to 1.8) 0.862 1.1 (0.4 to 3.1) 0.828 0.9 (0.5 to 1.7) 0.784
 Blue tan ****     0.7 (0.1 to 3.1)***** 0.605
 Red tan       
 Blue black       
 Blue mottled       
 Red mottled       
Base colour     0.886   0.876
 Blue Reference category   Reference category   Reference category  
 Red 1.1 (0.6 to 1.8) 0.853 0.8 (0.4 to 2.0) 0.704 1.0 (0.6 to 1.8) 0.876
Blue black tan     0.992   0.783
 No Reference category   Reference category   Reference category  
 Yes 1.0 (0.5 to 1.8) 0.922 1 (0.4 to 2.5) 0.958 0.9 (0.5 to 1.6) 0.789
Speckled     0.834   0.727
 No Reference category   Reference category   Reference category  
 Yes 1.1 (0.6 to 1.9) 0.756 0.8 (0.4 to 2.0) 0.681 1.1 (0.7 to 1.8) 0.733
Mask     <0.001   0.002
 No Reference category   Reference category   Reference category  
 Left 0.9 (0.4 to 2.1) 0.760 2.9 (0.8 to 10.1) 0.099 0.9 (0.4 to 2.2) 0.902
 Right 1.0 (0.4 to 2.6) 0.962 3.4 (0.7 to 17.0) 0.142 1.2 (0.5 to 2.7) 0.712
 Bilateral 0.2 (0.1 to 0.5) 0.001 0.5 (0.1 to 2.5) 0.425 0.2 (0.1 to 0.5) 0.001
Pigmented body spot     0.056   0.046
 None Reference category   Reference category   Reference category  
 At least one 0.4 (0.1 to 1.0) 0.052 0.3 (0.0 to 1.8) 0.176 0.4 (0.1 to 1.0) 0.044
White head/body patches     0.952   0.899
 No Reference category   Reference category   Reference category  
 Yes 0.9 (0.2 to 4.3) 0.892 1.3 (0.2 to 11.2) 0.784 0.9 (0.2 to 3.4) 0.905
Sire CHSD status     <0.001   0.209
 Normal tested by first-named author Reference category   Reference category   Reference category  
 Unilateral left 4.1 (1.5 to 11.1) 0.006 6.0 (1.7 to 20.9) 0.005 3.2 (0.5 to 19.1) 0.203
  1. *Standard errors adjusted for clustering by litter.
  2. ** Multinomial cumulative proportion animal ‘threshold’ models using the full pedigree (ie all pedigree data that were available), with dog fitted as a random effect.
  3. *** Bolded P-values are overall Wald P-values; unbolded P-values are Wald P-values for each coefficient.
  4. **** Last 5 categories excluded from analysis as none of these dogs had both ears affected.
  5. ***** Last 5 categories were pooled for analyses.
  6. † 95% CI indicates 95% confidence interval.