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Table 3 Univariable relative risk ratios and odds ratios for each of having one or two ears affected by congenital hereditary sensorineural deafness (CHSD) rather than no ears affected in Australian Cattle Dogs from multinomial logistic models and cumulative proportion animal models

From: Prevalence of congenital hereditary sensorineural deafness in Australian Cattle Dogs and associations with coat characteristics and sex

Variable

Multinomial logistic model*

Multinomial cumulative proportion animal model**

 

One ear affected

Two ears affected

Odds ratio (95% CI)†

P-value***

 

Relative risk ratio (95% CI)†

P-value***

Relative risk ratio (95% CI)†

P-value***

Sex

   

0.155

 

0.069

 Male

Reference category

 

Reference category

 

Reference category

 

 Female

1.7 (1.0 to 2.8)

0.056

1.4 (0.6 to 3.0)

0.447

1.6 (1.0 to 2.5)

0.067

Colour

   

0.913

 

0.940

 Red

Reference category

 

Reference category

 

Reference category

 

 Blue

0.9 (0.4 to 2.1)

0.857

1.5 (0.6 to 4.2)

0.402

1.1 (0.5 to 2.2)

0.878

 Blue black tan

0.9 (0.5 to 1.8)

0.862

1.1 (0.4 to 3.1)

0.828

0.9 (0.5 to 1.7)

0.784

 Blue tan

****

   

0.7 (0.1 to 3.1)*****

0.605

 Red tan

      

 Blue black

      

 Blue mottled

      

 Red mottled

      

Base colour

   

0.886

 

0.876

 Blue

Reference category

 

Reference category

 

Reference category

 

 Red

1.1 (0.6 to 1.8)

0.853

0.8 (0.4 to 2.0)

0.704

1.0 (0.6 to 1.8)

0.876

Blue black tan

   

0.992

 

0.783

 No

Reference category

 

Reference category

 

Reference category

 

 Yes

1.0 (0.5 to 1.8)

0.922

1 (0.4 to 2.5)

0.958

0.9 (0.5 to 1.6)

0.789

Speckled

   

0.834

 

0.727

 No

Reference category

 

Reference category

 

Reference category

 

 Yes

1.1 (0.6 to 1.9)

0.756

0.8 (0.4 to 2.0)

0.681

1.1 (0.7 to 1.8)

0.733

Mask

   

<0.001

 

0.002

 No

Reference category

 

Reference category

 

Reference category

 

 Left

0.9 (0.4 to 2.1)

0.760

2.9 (0.8 to 10.1)

0.099

0.9 (0.4 to 2.2)

0.902

 Right

1.0 (0.4 to 2.6)

0.962

3.4 (0.7 to 17.0)

0.142

1.2 (0.5 to 2.7)

0.712

 Bilateral

0.2 (0.1 to 0.5)

0.001

0.5 (0.1 to 2.5)

0.425

0.2 (0.1 to 0.5)

0.001

Pigmented body spot

   

0.056

 

0.046

 None

Reference category

 

Reference category

 

Reference category

 

 At least one

0.4 (0.1 to 1.0)

0.052

0.3 (0.0 to 1.8)

0.176

0.4 (0.1 to 1.0)

0.044

White head/body patches

   

0.952

 

0.899

 No

Reference category

 

Reference category

 

Reference category

 

 Yes

0.9 (0.2 to 4.3)

0.892

1.3 (0.2 to 11.2)

0.784

0.9 (0.2 to 3.4)

0.905

Sire CHSD status

   

<0.001

 

0.209

 Normal tested by first-named author

Reference category

 

Reference category

 

Reference category

 

 Unilateral left

4.1 (1.5 to 11.1)

0.006

6.0 (1.7 to 20.9)

0.005

3.2 (0.5 to 19.1)

0.203

  1. *Standard errors adjusted for clustering by litter.
  2. ** Multinomial cumulative proportion animal ‘threshold’ models using the full pedigree (ie all pedigree data that were available), with dog fitted as a random effect.
  3. *** Bolded P-values are overall Wald P-values; unbolded P-values are Wald P-values for each coefficient.
  4. **** Last 5 categories excluded from analysis as none of these dogs had both ears affected.
  5. ***** Last 5 categories were pooled for analyses.
  6. † 95% CI indicates 95% confidence interval.
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BMC Veterinary Research

ISSN: 1746-6148

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