Genetically similar strains of Escherichia coliO157:H7 isolated from sheep, cattle and human patients

BMC Veterinary Research

Table 1 Virulence genes, PFGE and MLVA profiles of VTEC O157:H7 isolated from Swedish sheep

PFGE type	Source¹	Year	vtx-genes²	eaeA	hlyA	cdtV-B	Clade 8³	LSPA-6	MLVA profile⁴	Exact matches
K	PS / M	2007	1,2c	+	+	-	-	213111	15-8-14-3-9-7-5-10	PFGE: Human 2008
Va	PS / I	2008	1	+	+	-	-	213111	NA-7-16-5-9-6-5-11
Vb	PS / I	2007	1, 2c^INS	+	+	-	-	213111	NA-7-15-5-9-6-5-11
La	PS / E	2008	2c	+	+	-	-	211111	5-7-14-4-6-6-NA-5
Lb	PS / E	2008	2c	+	+	-	-	211111	4-7-NA-5-3-9-5-8
Lc	PS / E	2008	2,2c	+	+	-	+	211111	17-7-20-4-4-7-8-5
Ld	PS / E	2008	2c	+	+	-	-	223323	14-7-11-3-4-5-9-6	PFGE: Human 2003, Cattle 2005 (x7)
Ld	PS / E	2008	2c	+	+	-	-	223323	14-7-11-3-4-5-9-6	PFGE: Human 2003, Cattle 2005 (x7)
Sa	PS / R	2008	2c	+	+	+	-	211111	5-7-12-4-6-6-7-5
Sb	PS / R	2008	2c	+	+	+	-	211111	5-7-13-4-9-6-7-5
Sb	PS / R	2008	2c	+	+	+	-	211111	5-7-13-4-9-6-7-5
Y	H / M	2004	2c	+	+	+	-	211111	5-7-14-4-6-6-6-5	MLVA: Cattle 2008 (x2)
T	H / M	2006	1,2c	+	+	-	-	213111	NA-7-10-3-8-7-5-7
E	H / M	2009	2c	+	+	-	-	223323	22-8-11-3-4-5-6-6

¹Sources are specified as the prevalence study (PS) or farms linked to human cases of illness (H), and by county, where M = Halland, I = Gotland, E = Östergötland and R = Skaraborg.
²2c = Stx2c-O157-FLY16; 2 = Stx2-O157-EDL933. ^INS = IS1209v-like insert in the gene.
³Clade 8 status of isolates assessed by SNP analysis for SNP539.
⁴NA = no amplicon for this locus.

ISSN: 1746-6148