Evolution of a multifactorial questionnaire (MFQ) in osteoarthritic dogs fed subsequentially with control and green-lipped mussel-enriched diets. MFQ-NRS: MFQ-Numerical Rating Scale, MFQ-S: MFQ-Static, MFQ-D: MFQ-Dynamic, MFQ-RTx: MFQ-Response to Treatment. Data are represented as median, 25th to 75th percentile at day(D)0, D30, and D90. General linear mixed model for repeated measures: (a) was significant difference of Least Squares Means when compared with D0. Multinomial logistic regression for repeated measures: *significant odds ratio (D0 vs D30). Significance was reached at P-value lower than 0.017 with Bonferroni’s adjustment.