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Table 5 HI titer of serum samples obtained from chickens inoculated with various plasmid DNAs in Trial 2

From: Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses

DNAs-inoculated groups

HI GMT

Weeks post inoculation

3*

4

6

Control

0

0

0

pDisplay

0

0

0

pDis/H5

2.69 ± 1.45

3.28 ± 1.40

3.28 ± 1.40

pDis/H5 + pDis/IL-15

3.62 ± 1.30c

16.00 ± 0.00a c

11.89 ± 1.45a c

pDis/H5 + pDis/IL-18

2.21 ± 1.30

6.56 ± 1.95b

4.42 ± 1.87

  1. * Chickens were given a booster 3 weeks after initial inoculation. Statistically significant differences (P < 0.05) are indicated by a, pDis/H5 compared with pDis/H5 + pDis/IL-15; b, pDis/H5 compared with pDis/H5 + pDis/IL-18; c, pDis/H5 + pDis/IL-15 compared with pDis/H5 + pDis/IL-18.
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BMC Veterinary Research

ISSN: 1746-6148

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