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Table 5 HI titer of serum samples obtained from chickens inoculated with various plasmid DNAs in Trial 2

From: Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses

DNAs-inoculated groups HI GMT
Weeks post inoculation
3* 4 6
Control 0 0 0
pDisplay 0 0 0
pDis/H5 2.69 ± 1.45 3.28 ± 1.40 3.28 ± 1.40
pDis/H5 + pDis/IL-15 3.62 ± 1.30c 16.00 ± 0.00a c 11.89 ± 1.45a c
pDis/H5 + pDis/IL-18 2.21 ± 1.30 6.56 ± 1.95b 4.42 ± 1.87
  1. * Chickens were given a booster 3 weeks after initial inoculation. Statistically significant differences (P < 0.05) are indicated by a, pDis/H5 compared with pDis/H5 + pDis/IL-15; b, pDis/H5 compared with pDis/H5 + pDis/IL-18; c, pDis/H5 + pDis/IL-15 compared with pDis/H5 + pDis/IL-18.