A comparative study of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuisin experimentally infected pigs

Agdestein, Angelika; Johansen, Tone B; Kolbjørnsen, Øyvor; Jørgensen, Anne; Djønne, Berit; Olsen, Ingrid

doi:10.1186/1746-6148-8-11

Table 1 Pathological and bacteriological findings in pigs inoculated with Mycobacterium avium subsp.

From: A comparative study of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuisin experimentally infected pigs

	Mycobacterium aviumsubsp. hominissuis
Time after inoculation	6 weeks																				8 weeks				12 weeks
Animal no	#1				#2				#3				#4				#5				#6				#7				#8				#9				#10
	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p
Lnn. mandibulares	-	-	+	+	-	-	+	-	-	-	+	-	-	-	+	+	-	-	+	-	-	-	+	+	+	+*	+	-	-	+	+	+	+	+*	+	+	-	+*	+	+
Tonsils	-	+*	+	+	-	-	+	+	-	-	+	+	-	-	+	+	-	-	+	+	-	-	+	-	-	-	+	-	-	-	C	+	-	+*	+	+	-	+*	+	-
Lnn. bifurcationis sinn.	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	-	+
Lung	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	nd	-	-	-	-
Spleen	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	nd	-	-	-	+
Liver	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	+	-	+	+	+*	-	nd	-	-	-	+
Lnn. jejunales	-	-	+	+	-	-	+	+	-	+*	+	+	-	-	+	+	-	+*	-	-	-	+*	+	+	+	+*	+	+	+	+*	+	+	+	+*	+	nd	-	+*	+	-
Lnn. ileocolici	-	-	+	-	-	-	+	+	-	-	-	-	-	-	+	-	-	-	-	-	-	-	+	-	+	+*	+	+	-	+*	+	+	+	+*	+	nd	-	+	-	-
Lnn. colici	-	-	+	-	-	-	+	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	+	+*	+	+	+	+*	+	nd	-	-	-	-
Jejunal Peyer's patches	-	-	+	-	-	-	-	-	-	-	-	-	-	-	+	+	-	-	+	-	-	-	-	nd	-	+	-	-	-	+	-	-	-	+	-	nd	-	-	-	-
Ileal Peyer's patches	-	-	+	+	-	-	+	-	-	-	+	-	-	+	+	+	-	-	-	-	-	-	+	nd	-	+	-	-	-	-	-	-	-	+*	-	nd	-	+	-	-
Faeces	nd	nd	+	nd	nd	nd	+	nd	nd	nd	+	nd	nd	nd	+	nd	nd	nd	-	nd	nd	nd	+	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd
	*Mycobacterium avium* subsp. *avium*
Time after inoculation	6 weeks																			12 weeks
Animal no	#11			#12				#13				#14				#15				#16				#17				#18				#19				#20
	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	p	m	h	c	P
Lnn. mandibulares	-	+*	+	+	-	+	+	-	-	-	+	-	-	-	-	-	-	-	+	-	-	-	+	-	-	-	+	+	-	+	+	-	-	+*	+	-	-	+*	+	+
Tonsils	-	+	-	+	-	-	-	-	-	-	-	-	-	-	-	+	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+*	+	+	-	+*	+	+
Lnn. bifurcationis sinn.	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	-	-	-	+
Lung	-	-	-	-	-	-	-	-	-	-	-	+	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	-	+	-	+	-	+
Spleen	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	+	-	-	-	+
Liver	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-	-	-	+	-	-	-	-	-	+	-	-	-	-	-	+
Lnn. jejunales	-	-	+	+	-	-	+	-	-	-	+	-	-	-	+	-	-	-	+	+	-	-	-	-	-	-	+	-	+	+*	+	-	+	+*	+	+	-	+	+	+
Lnn. ileocolici	+	+	+	+	-	-	+	+	-	-	-	-	-	-	+	-	-	-	+	-	-	-	-	-	-	-	-	-	-	+	+	-	+	+	+	+	-	-	+	-
Lnn. colici	-	-	-	+	-	-	+	-	-	+	-	-	-	-	-	-	-	-	+	+	-	-	+	-	-	-	+	-	-	-	-	+	-	-	-	-	-	-	+	-
Jejunal Peyer's patches	-	-	+	+	-	-	+	-	-	+	+	-	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	+	-	+	*	+	-	+	-	-	-	+
Ileal Peyer's patches	-	-	+	+	-	+*	+	-	-	-	+	+	-	-	-	-	-	-	+	-	-	+	+	+	-	-	-	-	-	+	+	-	-	+	-	+	-	+*	+	-
Faeces	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd	nd	nd	-	nd

hominissuis or Mycobacterium avium subsp. avium
m = macroscopic examination. Positive when visible tuberculous lesions are present
h = histopathological examination. Positive when granulomatous lesions present. * indicates the presence of acid-fast bacilli
c = cultural examination: Positive when acid-fast staining, characteristic colonies are present
p = real time PCR: Positive at Ct values ≤ 38
nd = not done or not applicable
C = contaminated

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ISSN: 1746-6148

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