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Table 2 Characteristics of PH permeability of histologically intact skin

From: The percutaneous permeation of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept®) through skin of different species in vitro

Parameter

Cattle

Dog

Cat

Horse

 

Mean

STD

Mean

STD

Mean

STD

Mean

STD

Jmax (μg/cm2/h)

1231.04

162.65

392.06

159.09

580.87

379.56

1298.78

178.97

Papp (cm/s)

1.71E-05

2.26E-06

5.45E-06

2.21E-06

8.07E-06

5.27E-06

1.80E-05

2.49E-06

Recovery 6 h (%)

13.25

1.86

5.88

2.28

6.00

2.35

28.36

3.48

Recovery 28 h (%)

37.01

2.18

38.80

15.68

35.09

15.79

61.10

1.64

  1. Flux Jmax, apparent permeability coefficient Papp, and recoveries after 6 and 28 hours of PH obtained in diffusion experiments with histologically intact split skin of different animals after 28 hours (n = 6) calculated from the maximum absorption according to Niedorf et al. (2008) [14]
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BMC Veterinary Research

ISSN: 1746-6148

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