|
Parameter
|
Cattle
|
Dog
|
Cat
|
Horse
|
|---|
| |
Mean
|
STD
|
Mean
|
STD
|
Mean
|
STD
|
Mean
|
STD
|
|---|
|
Jmax (μg/cm2/h)
|
1231.04
|
162.65
|
392.06
|
159.09
|
580.87
|
379.56
|
1298.78
|
178.97
|
|
Papp (cm/s)
|
1.71E-05
|
2.26E-06
|
5.45E-06
|
2.21E-06
|
8.07E-06
|
5.27E-06
|
1.80E-05
|
2.49E-06
|
|
Recovery 6 h (%)
|
13.25
|
1.86
|
5.88
|
2.28
|
6.00
|
2.35
|
28.36
|
3.48
|
|
Recovery 28 h (%)
|
37.01
|
2.18
|
38.80
|
15.68
|
35.09
|
15.79
|
61.10
|
1.64
|
- Flux Jmax, apparent permeability coefficient Papp, and recoveries after 6 and 28 hours of PH obtained in diffusion experiments with histologically intact split skin of different animals after 28 hours (n = 6) calculated from the maximum absorption according to Niedorf et al. (2008) [14]
