A genomics-informed, SNP association study reveals FBLN1 and FABP4 as contributing to resistance to fleece rot in Australian Merino sheep

Table 5 SNP association results for the difference between the post-wetting and the pre-wetting trials in three populations.

SNP	Armidale			Trangie Susceptible			Trangie Resistant
	ß	R²	P	ß	R²	P	ß	R²	P
ABCIn0150	-0.01	0.00	0.973	0.14	0.30	0.528	-0.03	0.03	0.841
ABCIn0270	-0.28	2.04	0.235	-0.32	1.32	0.307	0.00	0.00	0.993
ABCex0667	0.05	0.04	0.829	-0.22	0.61	0.276	0.09	0.32	0.388
FABIn20115	-0.21	0.58	0.361	n/a	n/a	n/a	n/a	n/a	n/a
FABIn20237	0.15	0.54	0.368	-0.46	2.78	0.041	0.09	0.40	0.386
FABIn30227	0.21	0.66	0.328	-0.22	0.05	0.781	0.44	0.33	0.472
FABIn30360	-0.13	0.40	0.409	0.54	3.50	0.012	-0.10	0.36	0.362
FABIn30420	0.21	0.36	0.472	-0.71	0.65	0.276	0.10	0.12	0.614
FAD1g20645	0.17	0.37	0.470	-0.14	0.12	0.676	-0.33	1.14	0.169
FBLIn100090	0.25	0.90	0.478	-0.32	1.22	0.684	-0.17	0.98	0.63
FBLIn120135	-0.19	0.72	0.359	0.23	0.54	0.353	-0.09	0.29	0.493
FBLIn120280	0.03	0.01	0.886	-0.12	0.18	0.596	0.04	0.06	0.711
FBLIn120995	0.52	5.71	0.005	-0.09	0.07	0.774	-0.06	0.10	0.729
FBLs10075	0.02	0.01	0.896	0.09	0.10	0.730	-0.14	0.87	0.285
HMGIn40390	-0.05	0.05	0.772	-0.18	0.46	0.343	0.02	0.01	0.861
HMGIn60110	0.00	0.00	0.985	0.03	0.01	0.906	0.11	0.36	0.387

Statistics are as follows: ß: Regression coefficient of fleece rot score on genotype (indicating the average change in fleece rot score for each copy of an allele); R²: Percentage of phenotypic variation explained by the SNP (%); P-value: Probability value associated with the test ß = 0. Statistics corresponding to significant associations are highlighted in bold type.

ISSN: 1746-6148