Table 4 Results of the discriminatory immunohistochemistry in historical TSE cases from passive surveillance.
Samples | ID | CNS region | Intraneuronal PrPd labeling | |
|---|---|---|---|---|
| Â | Â | Â | MAb R145 | MAb12B2 |
Controls | Classical scrapie | Obex | +++ | +++ |
| Â | BSEov - 1 | Obex | +++ | - |
| Â | BSEov - 2 | Spinal cord | +++ | - |
| Â | BSEov - 3 | Spinal cord | +++ | - |
| Â | TSE-negative | Obex | - | - |
Pre-surveillance | 15355 | Obex | +++ | +++ |
Passive surveillance | 21658 | Hippocampus | + | +++ |
| Â | 22614 | Midbrain | + | ++ - +++ |
| Â | 22805 | Midbrain, hippocampus | + | ++ |
| Â | 22856 | Obex | - | - |
| Â | 24058 | Cerebral cortex | - | - |
| Â | 30842 | Spinal cord | + - ++ | +++ |