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Table 4 Results of the discriminatory immunohistochemistry in historical TSE cases from passive surveillance.

From: Surveillance and simulation of bovine spongiform encephalopathy and scrapie in small ruminants in Switzerland

Samples ID CNS region Intraneuronal PrPd labeling
    MAb R145 MAb12B2
Controls Classical scrapie Obex +++ +++
  BSEov - 1 Obex +++ -
  BSEov - 2 Spinal cord +++ -
  BSEov - 3 Spinal cord +++ -
  TSE-negative Obex - -
Pre-surveillance 15355 Obex +++ +++
Passive surveillance 21658 Hippocampus + +++
  22614 Midbrain + ++ - +++
  22805 Midbrain, hippocampus + ++
  22856 Obex - -
  24058 Cerebral cortex - -
  30842 Spinal cord + - ++ +++