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Table 3 Complete set of historical TSE cases in small ruminants identified in Switzerland.

From: Surveillance and simulation of bovine spongiform encephalopathy and scrapie in small ruminants in Switzerland

Surveillance stream Case ID Year of Diagnosis Species Age
(years)
Sex PRNP
Genotype
Primary diagnosis Tested flock mates
- 15355 1981 goat 3 f nd scrapie1 -
passive 21658 1991 sheep 4 f nd scrapie1 18
  22614 1993 goat 2 f nd scrapie1 25
  22805 1993 sheep > 1.5 nr nd scrapie1 17
  22856 1993 sheep 6 f nd scrapie1 3
  24058 1995 sheep 1.5 f nd scrapie1 11
  30842 1999 sheep 3.5 m VRQ/VRQ scrapie2 19
  S7/CS 2004 sheep 6 f ARQ/ARQ atypical scrapie3 31
active G1/RS 2004 goat 10 f AHQ/AHQ atypical scrapie3 17
  G2/FS 2004 goat 12 m AHQ/AHQ atypical scrapie3 1
  S1/RS 2004 sheep nr f VRQ/VRQ classical scrapie3 42
  S2/RS 2004 sheep nr f ARR/ARR atypical scrapie3 169
  S3/RS 2004 sheep nr f ARR/ARR atypical scrapie3 3
  S4/RS 2004 sheep 10 f AHQ/AHQ atypical scrapie3 -
  S5/FS 2004 sheep 6 f AHQ/ARQ atypical scrapie3 30
  S6/FS 2005 sheep > 1.5 f ARR/ARR atypical scrapie3 16
  1. The primary diagnosis was established by state-of-the-art techniques at the year of confirmation and for cases identified before 2004 involved no means to discriminate BSE and atypical scrapie from classical scrapie.
  2. 1confimed by histopathology
  3. 2confimed by histopathology and immunohistochemistry
  4. 3confirmed by immunohistochemistry and subjected to biochemical TSE typing by Western immunoblot in a previous study [24].
  5. G, goat; S, sheep; RS, regularly slaughtered; FS, fallen stock; CS, clinical suspect; nd, not done; nr, not reported; f, female; m, male