Surveillance and simulation of bovine spongiform encephalopathy and scrapie in small ruminants in Switzerland

BMC Veterinary Research

Table 3 Complete set of historical TSE cases in small ruminants identified in Switzerland.

Surveillance stream	Case ID	Year of Diagnosis	Species	Age (years)	Sex	PRNP Genotype	Primary diagnosis	Tested flock mates
-	15355	1981	goat	3	f	nd	scrapie¹	-
passive	21658	1991	sheep	4	f	nd	scrapie¹	18
	22614	1993	goat	2	f	nd	scrapie¹	25
	22805	1993	sheep	> 1.5	nr	nd	scrapie¹	17
	22856	1993	sheep	6	f	nd	scrapie¹	3
	24058	1995	sheep	1.5	f	nd	scrapie¹	11
	30842	1999	sheep	3.5	m	VRQ/VRQ	scrapie²	19
	S7/CS	2004	sheep	6	f	ARQ/ARQ	atypical scrapie³	31
active	G1/RS	2004	goat	10	f	AHQ/AHQ	atypical scrapie³	17
	G2/FS	2004	goat	12	m	AHQ/AHQ	atypical scrapie³	1
	S1/RS	2004	sheep	nr	f	VRQ/VRQ	classical scrapie³	42
	S2/RS	2004	sheep	nr	f	ARR/ARR	atypical scrapie³	169
	S3/RS	2004	sheep	nr	f	ARR/ARR	atypical scrapie³	3
	S4/RS	2004	sheep	10	f	AHQ/AHQ	atypical scrapie³	-
	S5/FS	2004	sheep	6	f	AHQ/ARQ	atypical scrapie³	30
	S6/FS	2005	sheep	> 1.5	f	ARR/ARR	atypical scrapie³	16

The primary diagnosis was established by state-of-the-art techniques at the year of confirmation and for cases identified before 2004 involved no means to discriminate BSE and atypical scrapie from classical scrapie.
¹confimed by histopathology
²confimed by histopathology and immunohistochemistry
³confirmed by immunohistochemistry and subjected to biochemical TSE typing by Western immunoblot in a previous study [24].
G, goat; S, sheep; RS, regularly slaughtered; FS, fallen stock; CS, clinical suspect; nd, not done; nr, not reported; f, female; m, male

ISSN: 1746-6148