A single vaccination with an inactivated bovine respiratory syncytial virus vaccine primes the cellular immune response in calves with maternal antibody

Table 2 BRSV specific cellular immune response (extinction values of IFN γ ELISA on stimulated whole blood samples after vaccination and challenge)

Time [days]◆:		0	28	35
Treatment group	Animal
Vaccinated	V1	0.057*	0.185	0.736
	V2	0.056	0.267	0.476
	V3	0.054		0.223
	V4	0.051	0.121	0.542
	V5	0.052	0.054	0.408
	Average^#	0.054^a	0.157^a	0.477 ^a
Unvaccinated	C1	0.055	0.059	0.099
	C2	0.052	0.060	0.214
	C3	0.056	0.055	0.106
	C4	0.057	0.060	0.067
	Average	0.055^a	0.059^a	0.121^b

◆ Calves were infected intranasally with live BRSV 28 days after vaccination with one dose of the inactivated BRSV-PI3-Mh combination vaccine.
*According to the information of the manufacturer of the assay, values above the cut-off level (0.207) have to be interpreted as positive - indicated by the bold letter type
^# Average values with different superscript letters are significantly different (p < 0.05) from each other.

ISSN: 1746-6148