Table 2 Individual signs in 346 goats assessed by the short protocol
From: Monitoring of clinical signs in goats with transmissible spongiform encephalopathies
Postmortem TSE status: CLINICAL SIGN | CNS + (N = 42) | LRS + (N = 35) | Negative (N = 269) | p-value |
|---|---|---|---|---|
Abnormalities in behaviour | ||||
Behaviour when handled | ||||
- Nervous/went down | 4.8% | 8.6% | 10.0% | ns |
- Dull/docile | 0% | 0% | 2.2% | ns |
Spontaneous startle | 2.4% | 0% | 0% | ns |
Teeth grinding | 2.4% | 0% | 0.4% | ns |
Abnormalities in sensation | ||||
Hand clap1 | ||||
- Startle once | 2.4% | 0% | 0.7% | ns |
- Startle more than twice | 2.4% | 0% | 1.5% | ns |
Scratch test | ||||
- Positive | 4.8% | 2.9% | 0.4% | 0.04 |
- Unable to test | 0% | 11.4% | 4.1% | ns |
- Inconclusive | 0% | 0% | 2.2% | ns |
Hair loss | 54.8% | 57.1% | 42.0% | 0.04 |
Poll | 45.2% | 42.9% | 23.0% | 0.0005 |
Lateral neck | 9.5% | 5.7% | 6.7% | ns |
Base of/dorsal neck | 9.5% | 5.7% | 6.7% | ns |
Nose | 7.1% | 2.9% | 7.1% | ns |
Eyelid | 2.4% | 2.9% | 1.1% | ns |
Side abdomen/flank/chest | 0% | 2.9% | 2.6% | ns |
Shoulder | 2.4% | 0% | 4.1% | ns |
Back/tail base | 2.4% | 0% | 3.3% | ns |
Rump | 2.4% | 0% | 2.6% | ns |
Leg | 2.4% | 0% | 0.7% | ns |
Skin abnormalities | 26.2% | 28.6% | 12.3% | 0.002 |
Hair short | 19.0% | 8.6% | 27.9% | 0.02 |
Lateral neck | 11.9% | 2.9% | 18.6% | 0.02 |
Base of/dorsal neck | 4.8% | 0% | 1.1% | ns |
Back/tail base | 2.4% | 0% | 3.3% | ns |
Shoulder | 2.4% | 0% | 4.8% | ns |
Poll | 0% | 2.9% | 0.4% | ns |
Nose | 0% | 2.9% | 1.9% | ns |
Rump | 0% | 0% | 1.5% | ns |
Eyelid | 0% | 0% | 0.4% | ns |
Side abdomen/flank | 0% | 0% | 0.4% | ns |
Menace response1 | ||||
- Exaggerated | 4.8% | 2.9% | 4.5% | ns |
- Absent | 2.4% | 0% | 2.2% | ns |
Abnormalities in posture and movement | ||||
Ataxia/hypermetria2 | 4.8% | 2.9% | 0.7% | ns |
Abnormal posture | 2.4% | 2.9% | 1.5% | ns |
Tremor | ||||
- Head/body | 7.1% | 5.7% | 6.3% | ns |
- Limbs | 5.0% | 2.9% | 0.7% | ns |
Other signs | ||||
BCS poor (≤2)3 | 4.8% | 2.9% | 22.8% | 0.0001 |