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Table 2 Individual signs in 346 goats assessed by the short protocol

From: Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

Postmortem TSE status:
CLINICAL SIGN
CNS +
(N = 42)
LRS +
(N = 35)
Negative
(N = 269)
p-value
Abnormalities in behaviour     
Behaviour when handled     
- Nervous/went down 4.8% 8.6% 10.0% ns
- Dull/docile 0% 0% 2.2% ns
Spontaneous startle 2.4% 0% 0% ns
Teeth grinding 2.4% 0% 0.4% ns
Abnormalities in sensation
Hand clap1     
- Startle once 2.4% 0% 0.7% ns
- Startle more than twice 2.4% 0% 1.5% ns
Scratch test     
- Positive 4.8% 2.9% 0.4% 0.04
- Unable to test 0% 11.4% 4.1% ns
- Inconclusive 0% 0% 2.2% ns
Hair loss 54.8% 57.1% 42.0% 0.04
   Poll 45.2% 42.9% 23.0% 0.0005
   Lateral neck 9.5% 5.7% 6.7% ns
   Base of/dorsal neck 9.5% 5.7% 6.7% ns
   Nose 7.1% 2.9% 7.1% ns
   Eyelid 2.4% 2.9% 1.1% ns
   Side abdomen/flank/chest 0% 2.9% 2.6% ns
   Shoulder 2.4% 0% 4.1% ns
   Back/tail base 2.4% 0% 3.3% ns
   Rump 2.4% 0% 2.6% ns
   Leg 2.4% 0% 0.7% ns
Skin abnormalities 26.2% 28.6% 12.3% 0.002
Hair short 19.0% 8.6% 27.9% 0.02
   Lateral neck 11.9% 2.9% 18.6% 0.02
   Base of/dorsal neck 4.8% 0% 1.1% ns
   Back/tail base 2.4% 0% 3.3% ns
   Shoulder 2.4% 0% 4.8% ns
   Poll 0% 2.9% 0.4% ns
   Nose 0% 2.9% 1.9% ns
   Rump 0% 0% 1.5% ns
   Eyelid 0% 0% 0.4% ns
   Side abdomen/flank 0% 0% 0.4% ns
Menace response1     
- Exaggerated 4.8% 2.9% 4.5% ns
- Absent 2.4% 0% 2.2% ns
Abnormalities in posture and movement
Ataxia/hypermetria2 4.8% 2.9% 0.7% ns
Abnormal posture 2.4% 2.9% 1.5% ns
Tremor     
- Head/body 7.1% 5.7% 6.3% ns
- Limbs 5.0% 2.9% 0.7% ns
Other signs     
BCS poor (≤2)3 4.8% 2.9% 22.8% 0.0001
  1. Only tested in 344 goats1, 345 goats2, 342 goats3.
  2. ns = not significant (p > 0.5).