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Table 3 List of significant modulated genes (p < 0.05) expressed in the muscles suffering from PSSM.

From: Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions

Gene name EST – Sequence Entrez Gene Normalized ratio P-value < 0.05
IL18 Y11131 3606 6.20 1.58E-03
CTSS CD464451 1520 3.17 3.24E-03
LUM CX594607 4060 3.15 8.40E-04
CD44 CD464887 960 2.42 9.56E-04
FN1 ECU52108 2335 2.17 5.10E-03
GSTO1 CX603867 9446 2.03 2.64E-03
VCAM1 CX602484 7412 1.98 2.76E-02
ITGB1 CX598727 3688 1.87 2.31E-03
CXCR4 CD466324 7852 1.81 2.74E-02
HIF1A CX602270 3091 1.73 1.36E-03
ITGB2 CD535228 3689 1.70 4.26E-04
HSPA5 CX604607 3309 1.69 1.42E-02
GNAS BM734975 2778 1.63 1.45E-03
CD69 CD528606 969 1.62 2.67E-02
LTF ECA010930 4057 1.58 1.73E-02
GSK3B CX592808 2932 1.50 2.60E-03
APP CX601350 351 1.40 1.04E-02
CAT CD464332 847 1.39 6.36E-03
ENO1 CX603657 2023 1.39 7.60E-03
VAV1 BI961759 7409 1.37 2.70E-03
MYLK CX592941 4638 1.35 5.21E-02
EPO AB100030 2056 1.34 6.91E-03
IL15 AY682849 3600 1.34 4.57E-03
ITGAL CD464254 3683 1.32 1.32E-02
CD40 AY514017 958 1.30 4.73E-02
ACTN2 AB178951 88 1.29 1.76E-02
GDF8 AB033541 2660 1.29 4.87E-02
DAG1 CX600578 1605 1.28 1.20E-02
IGF2 U11241 3481 1.28 2.61E-02
HCK BM734694 3055 1.27 2.45E-02
ACAA2 CX603916 10449 1.25 1.67E-02
COMT AB178284 1312 1.23 4.70E-04
FLII CX604876 2314 1.21 2.73E-02
ATP5a1 DN509143 498 1.21 5.18E-02
MYL9 CX594102 10398 1.18 1.56E-02
CCL13 ECA251188 6357 1.17 1.04E-02
GJA5 AY008788 2702 1.07 5.07E-02
ATP5C1 CX593263 509 0.90 4.87E-02
PYGL CX597788 5836 0.90 2.66E-02
FGR CD470584 2268 0.88 4.71E-02
MRPL49 CD469126 740 0.87 5.00E-02
GOT2 CX602317 2806 0.87 4.82E-02
ALOX5AP CD536322 241 0.86 1.95E-02
IMMT CX597479 10889 0.85 4.56E-02
ECHS1 CX604357 1892 0.85 4.05E-03
SLC2A1 DQ139875 6513 0.85 6.96E-03
CYTB X79547 4519 0.85 1.98E-02
EDN1 AY730629 1906 0.84 4.03E-02
PNMT AB071422 5409 0.84 2.08E-03
IL7 CX592622 3574 0.84 4.32E-02
IDH2 CX604713 3418 0.83 1.09E-02
PTGER4 DN505656 5734 0.83 1.72E-05
IL6ST DN507511 3572 0.83 4.34E-04
SCN4A ECU25990 6329 0.82 3.11E-02
CEBPB CX605423 1051 0.82 8.99E-03
SHMT2 CX605845 6472 0.82 2.08E-03
GLS CX600244 2744 0.81 7.01E-03
CYP19A1 ECA012610 1588 0.81 3.23E-02
PLAU CD471288 5328 0.81 3.89E-03
SLC25a5 DN506810 292 0.81 5.66E-03
ATP5o DN509617 539 0.80 1.98E-02
NQO1 DN508254 1728 0.80 2.44E-04
FYN CD528430 2534 0.78 1.17E-02
SLC8A1 DQ178640 6546 0.78 1.98E-03
HNRPK CX598401 3190 0.77 4.69E-05
Leu-ARNt_TRNL1 X79547 4567 0.77 1.58E-03
MIF CX599697 4282 0.77 1.05E-02
ND2 X79547 4536 0.76 3.34E-03
CYTB X79547 4519 0.76 7.85E-03
OPRM1 ECA519535 4988 0.76 1.07E-04
CSF1 CD469550 1435 0.75 7.13E-04
RELB CD472197 5971 0.75 5.86E-05
Met-ARNt_TRNM X79547 4569 0.74 3.31E-03
SSPN CX605718 8082 0.72 1.65E-02
COX 3 X79547 4514 0.72 5.08E-03
CPT2 CX599757 1376 0.72 1.49E-04
PDE4B CD470720 5142 0.72 4.70E-06
ATP5e DN509652 514 0.72 1.22E-02
NR3C1 CX597756 2908 0.72 1.89E-02
STAT6 CD467276 6778 0.72 1.91E-02
ND2 X79547 4536 0.72 1.09E-04
COX 3 X79547 4514 0.70 2.46E-03
ND6 X79547 4541 0.70 4.69E-05
OXTR BM734870 5021 0.69 9.30E-04
ATP1B1 DN511201 481 0.69 2.20E-04
ATP5j DN507306 522 0.69 4.03E-02
PLG BM780461 5340 0.69 3.21E-04
COX 2 X79547 4513 0.69 1.03E-02
PKM2 CX604027 5315 0.69 1.82E-02
ATP5h CX599509 10476 0.69 1.20E-03
ATP5d CX603287 513 0.69 4.65E-04
CSF3 AF503365 1440 0.68 1.84E-05
Phe-ARNt_TRNF X79547 4558 0.67 4.07E-05
Glu-ARNt_TRNE X79547 4556 0.67 2.98E-06
TNFRSF4 CD465063 7293 0.66 6.88E-04
IGHE ECA305046 3497 0.66 4.10E-05
ATP5l CX603854 10632 0.66 4.69E-03
UCP2 CD528532 7351 0.66 8.40E-03
Lys-ARNt_TRNK X79547 4566 0.65 1.60E-03
ND3 X79547 4537 0.64 1.12E-03
ND6 X79547 4541 0.63 7.60E-05
ATP2A1 AF489278 487 0.62 5.98E-04
TNFSF13B CD470712 10673 0.62 1.95E-05
Gly-ARNt_TRNG X79547 4563 0.62 4.97E-03
NFKBIB CX601294 4793 0.59 9.31E-06
PLCG2 CX603458 5336 0.58 7.89E-08
ND5 X79547 4540 0.57 1.01E-05
ND3 X79547 4537 0.57 1.65E-05
SLC25a17 CX598253 10478 0.57 2.13E-06
SRI DN506802 6717 0.57 4.60E-06
Val-ARNt_TRNV X79547 4577 0.56 1.95E-04
Asp-ARNt_TRND X79547 4555 0.55 1.76E-05
ND5 X79547 4540 0.54 1.39E-05
PDE4D CX593241 5144 0.54 1.26E-06
Ser-ARNt_TRNS2 X79547 4575 0.50 6.05E-03
Ile-ARNt_TRNI X79547 4565 0.49 1.21E-03
SLC25a15 CX598538 10166 0.48 4.95E-02
Leu-ARNt_TRNL2 X79547 4568 0.44 1.13E-05
Trp-ARNt_TRNW X79547 4578 0.40 2.13E-06
Thr-ARNt_TRNT X79547 4576 0.40 5.63E-05
Pro-ARNt_TRNP X79547 4571 0.39 2.59E-06
VEGF AB053350 7422 0.37 1.32E-06
PRKCA CX602892 5578 0.37 2.18E-06
SLC2A2 AJ715983 6514 0.35 2.18E-06
Ala-ARNt_TRNA X79547 4553 0.35 1.10E-04
Tyr-ARNt_TRNY X79547 4579 0.35 1.04E-03
Asn-ARNt_TRNN X79547 4570 0.33 8.13E-06
Cys-ARNt_TRNC X79547 4511 0.28 4.48E-06
Gln-ARNt_TRNQ X79547 4572 0.21 3.81E-07
  1. Significant p-value (p < 0.05) indicated that the expression ratio was significantly different from 1.
  2. P-values are expressed in scientific format: 1E-3 means 1.10-3.