Figure 1From: Biomarkers for ragwort poisoning in horses: identification of protein targetsChemical structure of pyrrolizidine alkaloids. Jacobine is one of the major pyrrolizidine alkaloids found in ragwort. The related pyrrolizidine alkaloid, monocrotaline was used in the experimental procedures of this study. Monocrotaline was chemically oxidised to its pyrrolic derivative, dehydromonocrotaline (DHM) and exposed to equine plasma proteins.Back to article page