Table 3 Significantly up-regulated genes in mammary tissue challenged with S. aureus.
Function | Gene symbol | Genbank accession | Genbank description |
|---|---|---|---|
Chemokine, cytokine and intercellular signalling | Â | Â | Â |
| Â | CCL11 | NM_002986 | Homo sapiens chemokine (C-C motif) ligand 11 (CCL11), mRNA |
| Â | CCL2 | NM_174006 | Bos taurus chemokine (C-C motif) ligand 2 (CCL2), mRNA. |
| Â | CCL20 | NM_004591 | Homo sapiens chemokine (C-C motif) ligand 20 (CCL20), mRNA |
| Â | CCL3L1 | NM_021006 | Homo sapiens chemokine (C-C motif) ligand 3-like 1 (CCL3L1), mRNA |
| Â | CCL4L1 | AY575854 | Homo sapiens similar to cytokine (LOC388372), mRNA |
| Â | CSF3 | NM_172219 | Homo sapiens colony stimulating factor 3 (granulocyte) (CSF3), transcript variant 2, mRNA |
| Â | CXCL1 | NM_001511 | Homo sapiens chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, |
| Â | CXCL2 | NM_002089 | Homo sapiens chemokine (C-X-C motif) ligand 2 (CXCL2), mRNA |
| Â | CXCL10 | AB070717 | Homo sapiens chemokine (C-X-C motif) ligand 10 (CXCL10), mRNA |
| Â | IL1B | NM_174093 | Bos taurus interleukin 1, beta (IL1B), mRNA. |
| Â | IL6 | NM_001009392 | Ovis aries interleukin 6 (IL6), mRNA |
| Â | IFNG | NM_174086 | interferon-gamma; Bos taurus interferon, gamma or immune type [interferon gamma type 2] |
| Â | IL8 | NM_173925 | Bos taurus interleukin 8 [neutrophil activating peptide 1] (IL8), mRNA. |
| Â | LEP | NM_173928 | Bos taurus leptin [obesity] (LEP), mRNA |
| Â | PLAUR | NM_174423.2 | Homo sapiens plasminogen activator, urokinase receptor (PLAUR), mRNA |
| Â | PTX3 | NM_002852 | Homo sapiens pentaxin-related gene, rapidly induced by IL-1 beta (PTX3), mRNA |
| Â | S100A12 | NM_174651 | Bos taurus S100 calcium binding protein A12 (calgranulin C) (S100A12), mRNA |
| Â | S100A2 | NM_005978 | Homo sapiens S100 calcium binding protein A2 (S100A2), mRNA |
| Â | THBS1 | NM_174196 | Homo sapiens thrombospondin 1 (THBS1), mRNA |
Cell surface receptors | Â | Â | Â |
| Â | CCR1 | NM_001295 | Homo sapiens chemokine (C-C motif) receptor 1 (CCR1), mRNA |
| Â | CD14 | NM_000591 | Homo sapiens CD14 antigen (CD14), mRNA |
| Â | CD40 | NM_152854 | Homo sapiens tumor necrosis factor receptor superfamily, member 5 (TNFRSF5), transcript |
| Â | CSF3R | NM_172313 | Homo sapiens colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant |
| Â | IL11RA | NM_147162 | Homo sapiens interleukin 11 receptor, alpha (IL11RA), transcript variant 2, mRNA |
| Â | SLC2A4 | NM_001042 | Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4) |
| Â | TLR2 | NM_003264 | Homo sapiens toll-like receptor 2 (TLR2), mRNA |
| Â | TLR4 | NM_138557 | Homo sapiens toll-like receptor 4 (TLR4), transcript variant 4, mRNA |
| Â | TNFRSF9 | NM_001561 | Homo sapiens tumor necrosis factor receptor superfamily, member 9 (TNFRSF9), mRNA |
Intracellular signaling | Â | Â | Â |
| Â | CDKN1A | NM_078467 | Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), transcript variant 2, mRNA |
| Â | FGD6 | AC009159 | Homo sapiens FYVE, RhoGEF and PH domain containing 6 (FGD6), mRNA |
| Â | MTMR10 | AJ567991 | Homo sapiens hypothetical protein FLJ20313 (FLJ20313), mRNA |
| Â | HCK | NM_002110 | Homo sapiens hemopoietic cell kinase (HCK), mRNA |
| Â | MARCKS | NM_002356 | Homo sapiens myristoylated alanine-rich protein kinase C substrate (MARCKS), mRNA |
| Â | MARCKSL1 | NM_023009 | Homo sapiens MARCKS-like protein (MLP), mRNA |
| Â | ZFYVE9 | NM_007324 | Homo sapiens MAD, mothers against decapentaplegic homolog (Drosophila) interacting |
Apoptosis | Â | Â | Â |
| Â | BAT3 | NM_174196 | Homo sapiens HLA-B associated transcript 3 (BAT3), transcript variant 3, mRNA |
| Â | BCL2A1 | NP_004040 | Homo sapiens BCL2-related protein A1 (BCL2A1), mRNA |
| Â | BIRC3 | NM_182962 | Homo sapiens baculoviral IAP repeat-containing 3 (BIRC3), transcript variant 2, mRNA |
| Â | IER3 | NM_003897 | Homo sapiens immediate early response 3 (IER3), transcript variant short, mRNA |
Transcription factor or regulator | Â | Â | Â |
| Â | ATF3 | NM_001674 | Homo sapiens activating transcription factor 3 (ATF3), mRNA |
| Â | BTG2 | NM_006763 | Homo sapiens BTG family, member 2 (BTG2), mRNA |
| Â | EGR1 | NM_001964 | Homo sapiens early growth response 1 (EGR1), mRNA |
| Â | FOS | NM_005252 | Homo sapiens v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS), mRNA |
| Â | JUNB | NM_002229 | Homo sapiens jun B proto-oncogene (JUNB), mRNA |
| Â | NFKB2 | NM_002502 | Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells |
| Â | NFKBIA | NM_020529 | Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor |
| Â | NR2F6 | AF338825 | Homo sapiens nuclear receptor subfamily 2, group F, member 6 (NR2F6), mRNA |
Assorted | Â | Â | Â |
| Â | ACSL6 | NM_015256 | Homo sapiens acyl-CoA synthetase long-chain family member 6 (ACSL6), mRNA |
| Â | FUT8 | NM_177501 | Homo sapiens fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (FUT8), transcript |
| Â | HSPA1A | NM_005345 | Homo sapiens heat shock 70 kDa protein 1A (HSPA1A), mRNA |
| Â | MGC21881 | XP_219130 | Homo sapiens hypothetical protein LOC286286 (LOC286286), mRNA |
| Â | NOS2A | NM_000625 | Homo sapiens nitric oxide synthase 2A (inducible, hepatocytes) (NOS2A), transcript variant |
| Â | SOD2 | L22092 | Homo sapiens superoxide dismutase 2, mitochondrial (SOD2), mRNA |
| Â | TIMP1 | NM_003254 | Homo sapiens tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase) |
| Â | TUBA1 | NM_006000 | Homo sapiens tubulin, alpha 1 (testis specific) (TUBA1), mRNA |
| Â | WARS | NM_174218 | Homo sapiens tryptophanyl-tRNA synthetase (WARS), mRNA |