Antimicrobial activity of rS100A12. Antimicrobial activities of rS100A12 were measured using the Broth Microdilution Susceptibility Testing Method. (a) E. coli and (b) S. aureus. (■), rS100A12; (▲) BSA at the same concentrations. Bars represent the means ± SEM for 2 replicates. The data were examined for significance using ANOVA and the asterisk denotes significant differences (P < 0.05) from the control.