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Table 2 Genotype, breed distribution with inoculation details and incubation periods of BSE-negative sheep

From: Pruritus is a common feature in sheep infected with the BSE agent

  Genotype Breed n Oral dose (at age) IP
Unchallenged (controls) ARQ/ARQ Romney 3 None 15, 21, 34
   Suffolk 2 None 3, 15
  ARQ/ARR Romney 4 None 10, 21, 33, 45
  ARR/ARR Romney 4 None 9, 21, 33, 45
   Suffolk 3 None 9, 34, 45
  TOTAL   16   
Challenged ARQ/ARQ Romney 5 5 g (6 months) 12 (1.22)
   Suffolk 7 5 g (4 months) 9 (2.4)
   Suffolk 1 0.5 g (6 months) 38
  ARQ/ARR Romney 17 5 g (6 months) 41 (6.7)
   Romney 1 0.05 g (6 months) 50
   Suffolk 13 5 g (4 months) 32 (6.1)
  ARR/ARR Romney 17 5 g (6 months) 42 (7.3)
   Suffolk 15 5 g (4 months) 29 (3.4)
  TOTAL   76   
  1. IP = Incubation period in months (always rounded down), defined as time period from inoculation to cull and – for unchallenged animals in the oral BSE pathogenesis study – from test group exposure and cull. The mean incubation period with the standard error in parentheses is given if the numbers exceed four.