From: Relevance of the regional lymph node in scrapie pathogenesis after peripheral infection of hamsters
Sham operation 6 days after infection | Ectomy 4 h after infection | Ectomy 24 h after infection | Ectomy 2 days after infection | Ectomy 6 days after infection | ||||||
---|---|---|---|---|---|---|---|---|---|---|
individual survival | mean ± SD | individual survival | mean ± SD | individual survival | mean ± SD | individual survival | mean ± SD | individual survival; | mean ± SD | |
Infectious dose: 20 μl 1% 263K-homogenate | 108; 108; 121; 121; 121; 121 | 117 ± 7 | 111; 111; 108; 114; 114; 118 | 113 ± 3; p ≤ 0.25 | 104; 108; 108; 111; 114; 114 | 110 ± 4 p ≤ 0.1 | 108; 111; 114; 114; 114; 118 | 113 ± 3 p ≤ 0.5 | 93; 108; 108; 111; 114; 118 | 109 ± 9; p ≤ 0.1 |
Infectious dose: 20 μl 0.01% 263K-homogenate | 108; 111; 115; 118 | 113 ± 4 | 100; 108; 111; 115; 118; 115 | 111 ± 7; p ≤ 1.0 | 111; 115; 118; 121; 174 | 128 ± 26; p ≤ 0.5 | 118; 118; 121; 132; 178 | 133 ± 26; p ≤ 0.25 | 115; 115; 125; 125; 128; 128 | 123 ± 6; p ≤ 0.05* |