Table 2 Linkage data between the merle phenotype and CFA10 markers. List of the CFA10 genotyped markers in the sub-pedigree (left), the complete pedigree (middle) and all the studied pedigrees (right), with their two point Lod scores and recombination fractions (θ). All markers were selected from CanFam 1.0 sequence draft except FH2293 and C10769 taken from Guyon et al.[13]. The markers are ordered in the table from the centromere to the telomere. ^a markers flanking the SOX10 gene. Values in bold correspond to the highest Lod scores obtained in the three conditions.

CFA10.1

3,109459–3,109703

0.00

6.32

6.31

6.22

5.79

5.23

4.64

4.02

2.68

CFA10.2

3,150322–3,150695

0.00

6.92

6.91

6.82

6.37

5.78

5.16

4.50

3.05

CFA10.3

3,169429–3,169640

0.00

3.01

3.01

2.95

2.72

2.42

2.10

1.76

1.06

CFA10.4

3,452451–3,452757

0.04

5.94

4.82

5.71

5.90

5.55

5.04

4.44

3.04

CFA10.5 ^c

3,533969–3,534312

0.00

6.92

6.91

6.81

6.35

5.73

5.09

4.40

2.90

CFA10.6

4,050670–4,050915

0.00

3.01

3.01

2.96

2.74

2.46

2.17

1.86

1.20

CFA10.7

4,901919–4,902276

0.00

7.23

7.21

7.11

6.65

6.04

5.39

4.71

3.20

CFA10.8

6,938580–6,938928

0.00

7.23

7.21

7.11

6.65

6.04

5.39

4.71

3.20

CFA10.9

8,539383–8,539710

0.50

0.00

-20.08

-11.15

-5.16

-2.85

-1.68

-0.98

-0.31

CFA10.10

9,459108–9,459324

0.07

2.62

1.21

2.15

2.60

2.57

2.40

2.16

1.52

CFA10.11

10,599594–10,599989

0.04

5.08

3.91

4.82

5.07

4.79

4.35

3.84

2.64

CFA10.12

12,963916–12,964094

0.15

2.55

-4.49

-0.58

1.79

2.43

2.55

2.44

1.83

CFA10.13

13,290922–13,291305

0.18

0.75

-2.99

-1.03

0.21

0.60

0.73

0.74

0.57

CFA10.14

13,687824–13,688059

0.11

3.44

-1.49

1.42

3.09

3.43

3.36

3.10

2.25

CFA10.15

15,287513–15,287805

0.14

2.22

-2.99

-0.06

1.69

2.15

2.21

2.08

1.51

CFA10.16

16,325750–16,325992

0.09

3.67

0.61

2.53

3.55

3.66

3.49

3.19

2.33

CFA10.17

16,883188–16,883575

0.12

2.95

-2.09

0.83

2.53

2.92

2.91

2.72

2.02

CFA10.18

17,574178–17,574420

0.08

3.87

0.91

2.82

3.79

3.84

3.61

3.25

2.31

CFA10.19

18,220318–18,220600

0.10

4.20

-0.58

2.31

3.93

4.20

4.07

3.74

2.75

CFA10.20

19,075239–19,075433

0.12

3.19

-1.79

1.12

2.81

3.17

3.13

2.90

2.10

CFA10.21

19,999011–19,999231

0.26

0.51

-11.69

-5.76

-1.88

-0.50

0.12

0.41

0.47

CFA10.22

21,607022–21,607316

0.10

4.45

-0.28

2.61

4.20

4.45

4.30

3.95

2.90

CFA10.23

21,956041–21,956337

0.10

4.45

-0.28

2.61

4.20

4.45

4.30

3.95

2.90

CFA10.24

23,113457–23,113656

0.25

0.92

-13.18

-6.27

-1.77

-0.17

0.52

0.83

0.85

CFA10.25

24,031569–24,031859

0.10

3.51

-1.19

1.70

3.28

3.51

3.34

2.97

1.93

CFA10.26

25,504535–25,504764

0.14

2.73

-4.19

-0.29

2.05

2.65

2.73

2.57

1.89

CFA10.27

25,930447–25,930692

0.12

1.84

-1.49

0.45

1.58

1.83

1.81

1.67

1.16

CFA10.28

26,491052–26,491288

0.13

1.66

-1.79

0.16

1.32

1.62

1.65

1.56

1.16

CFA10.29

27,391154–27,391817

0.18

2.36

-6.88

-1.98

1.09

2.04

2.33

2.33

1.87

CFA10.30

28,230039–28,230419

0.30

0.69

-18.28

-9.37

-3.47

-1.27

-0.23

0.33

0.69

CFA10.31^a

29,232270–29,232511

0.13

3.51

-3.28

0.61

2.90

3.46

3.49

3.27

2.45

CFA10.32^a

29,355913–29,355989

0.14

3.09

-3.88

0.02

2.37

2.99

3.08

2.94

2.24

CFA10.33^a

29,483066–29,483109

0.13

2.40

-2.69

0.23

1.95

2.37

2.38

2.22

1.58

CFA10.34^a

29,826073–29,826290

0.14

2.52

-2.69

0.24

2.00

2.45

2.51

2.38

1.81

CFA10.35^a

29,834441–29,834690

0.16

2.74

-6.28

-1.39

1.63

2.51

2.73

2.67

2.08

SOX10

29,856920–29,867728

CFA10.36^a

29,861299–29,861547

0.08

3.60

0.61

2.52

3.51

3.58

3.37

3.02

2.10

CFA10.37^a

29,868038–29,868267

0.14

3.38

-3.58

0.32

2.67

3.29

3.37

3.21

2.47

CFA10.38^a

30,176995–30,177378

0.11

3.65

-1.19

1.71

3.35

3.65

3.55

3.26

2.38

FH2293^a

31,696028–31,696274

0.13

3.56

-3.28

0.61

2.93

3.50

3.54

3.34

2.53

C10.769^a

36,663349–36,663563

0.18

1.50

-5.99

-2.06

0.42

1.20

1.46

1.49

1.18

CFA10.1

3,109459–3,109703

0.00

11.74

11.72

11.54

10.70

9.61

8.46

7.27

4.71

CFA10.2

3,150322–3,150695

0.02

11.97

11.13

11.91

11.63

10.64

9.48

8.20

5.38

CFA10.3

3,169429–3,169640

0.00

6.62

6.61

6.50

5.98

5.30

4.60

3.86

2.33

CFA10.4

3,452451–3,452757

0.03

13.82

11.73

13.46

13.65

12.67

11.36

9.88

6.55

CFA10.5 ^c

3,533969–3,534312

0.02

8.77

7.82

8.65

8.58

7.88

7.01

6.03

3.86

CFA10.6

4,050670–4,050915

0.00

6.92

6.91

6.79

6.24

5.51

4.76

3.99

2.41

CFA10.7

4,901919–4,902276

0.00

15.65

15.63

15.39

14.30

12.88

11.40

9.84

6.54

CFA10.8

6,938580–6,938928

0.02

14.90

14.13

14.87

14.39

13.16

11.72

10.17

6.76

CFA10.9

8,539383–8,539710

0.19

2.48

-14.38

-5.54

0.02

1.78

2.38

2.47

1.89

CFA10.1

3,109459–3,109703

0.04

10.67

8.43

10.21

10.61

9.91

8.91

7.74

5.09

CFA10.2

3,150322–3,150695

0.04

10.97

8.73

10.51

10.91

10.21

9.21

8.04

5.39

CFA10.3

3,169429–3,169640

0.00

6.02

6.01

5.91

5.44

4.84

4.22

3.56

2.20

CFA10.4

3,452451–3,452757

0.03

14.38

12.33

14.05

14.19

13.15

11.79

10.25

6.83

CFA10.5 ^c

3,533969–3,534312

0.02

8.77

7.82

8.65

8.58

7.89

7.02

6.05

3.90

CFA10.6

4,050670–4,050915

0.03

6.99

6.01

6.86

6.85

6.23

5.46

4.61

2.82

CFA10.7

4,901919–4,902276

0.00

19.87

19.83

19.52

18.11

16.28

14.37

12.37

8.15

CFA10.8

6,938580–6,938928

0.00

19.57

19.53

19.22

17.82

15.99

14.08

12.09

7.91

CFA10.9

8,539383–8,539710

0.16

4.23

-11.97

-3.16

2.25

3.83

4.22

4.10

3.02