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Table 2 Identification of copper-responsive proteins in Cambridge sheep. 2-D gels for each animal were run in triplicate and placed in analysis sets. Statistical analysis sets were created from two copper-challenged Cambridge (n = 6 gels) and North Ronaldsay (n = 6 gels) animals and statistically significant changes in protein expression were identified by Student's t-test at p ≤ 0.05.

From: A proteomics study of the response of North Ronaldsay sheep to copper challenge

Protein Identification Accession Species Mwt (kDa) Mowse score Blast score E value Seq coverage Fold change (%)
2a. Epoxide hydrolase [PIR:A47504] Mouse 62.6 - 29 9.3 (LG)ASLNTPFMQAVP 3
  [EMBL:AAS68016] Pig   - 25 238 SSDETFLTVSR  
   Several    25 142 (YQ)LPALAQ(FQ)R  
4. Heat shock protein Hsp 27 [Swiss-Prot:JC4244] Dog 22.9 86    29% N/A
5. Cytosolic NADP+-dependent isocitrate dehydrogenase [trEMBL:Q6XUZ5] Sheep 47.2 272    61% N/A
6. Methionine adenosyl transferase [Swiss-Prot:S06114] Rat 44.2 129    27% 2.6
  1. 2-D gels for each animal were run in triplicate and placed in analysis sets. Statistical analysis sets were created from two copper-challenged Cambridge and North Ronaldsay animals and statistically significant changes in protein expression were identified by Student's t-test at p ≤ 0.05.