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Table 1 Identification of copper-responsive proteins in North Ronaldsay sheep. 2-D gels for each animal were run in triplicate and placed in analysis sets. Statistical analysis sets were created from two copper-challenged Cambridge (n = 6 gels) and North Ronaldsay (n = 6 gels) animals and statistically significant changes in protein expression were identified by Student's t-test at p ≤ 0.05.

From: A proteomics study of the response of North Ronaldsay sheep to copper challenge

Protein Identification Accession Species Mwt (kDa) Mowse score Blast score E value Seq coverage Fold change
1. Cathepsin D [Swiss-Prot:Q9MZS8] Sheep 39.8   33 0.78 VSSLPQVTLK 4
2b Epoxide hydrolase [PIR:A47504] Mouse 62.6   35 0.1 (AV)ASLNTPFM N/A
  [EMBL:CAA46211.1] Rat    41 0.002 YQLPALAQAGFR  
3. Ferritin light chain [Uniref:O46415] Cow 19.9 112    31% 4
7. Peroxiredoxin 3 (SP-22) [PIR:JC2258] Cow 21.7 74    30% 10.0
   Rat 28.3   38 0.031 HLSVNDLPVGR  
8. Plasma retinol binding protein [PIR:S13186] Cow 21.4 130    30% 2.8
  1. 2-D gels for each animal were run in triplicate and placed in analysis sets. Statistical analysis sets were created from two copper-challenged Cambridge and North Ronaldsay animals and statistically significant changes in protein expression were identified by Student's t-test at p ≤ 0.05.